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Agreement between i...
Agreement between iFR and FFR in staged follow-up evaluation of non-culprit stenoses after ST-segment elevation myocardial infarction (iSTEMI substudy)
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- Thim, Troels (författare)
- Aarhus University Hospital, Aarhus, Denmark
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- Götberg, Matthias (författare)
- Department of Cardiology, Skåne University Hospital, Lund University, Lund, Sweden
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- Fröbert, Ole, 1964- (författare)
- Region Örebro län,Örebro universitet, Institutionen för medicinska vetenskaper
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- Nijveldt, Robin (författare)
- Radboud UMC, Nijmegen, Netherlands
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- van Royen, Niels (författare)
- Radboud University, Nijmegen, Netherlands
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- Baptista, Sergio (författare)
- Hospital Fernando Fonseca, Amadora, Portugal
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- Koul, Sasha (författare)
- Department of Cardiology, Skåne University Hospital, Lund University, Lund, Sweden
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- Kellerth, Thomas (författare)
- Örebro University Hospital, Örebro, Sweden
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- Botker, Hans Erik (författare)
- Aarhus University Hospital, Aarhus, Denmark
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- Christiansen, Evald (författare)
- Aarhus University Hospital, Aarhus, Denmark
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- Jakobsen, Lars (författare)
- Aarhus University Hospital, Aarhus, Denmark
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- Kristensen, Steen Dalby (författare)
- Aarhus University Hospital, Aarhus, Denmark
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- Maeng, Michael (författare)
- Aarhus University Hospital, Aarhus, Denmark
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(creator_code:org_t)
- Elsevier, 2017
- 2017
- Engelska.
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Ingår i: Journal of the American College of Cardiology. - : Elsevier. - 0735-1097 .- 1558-3597. ; 70:18, s. B91-B91
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- BACKGROUND: Classification agreement between instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) is approximately 80% in stable patients. It was recently shown that FFR guidance, as compared to iFR guidance, was associated with a higher risk of subsequent revascularization among patients with non- ST-segment elevation myocardial infarction. The classification agreement, and the impact of time interval, between iFR and FFR in the assessment of non-culprit lesions after recent ST-segment elevation myocardial infarction (STEMI) has not been described.METHODS: The iSTEMI study assessed agreement between iFR across non-culprit stenoses at the index procedure in patients with STEMI versus iFR and FFR at a follow-up angiography. The interval between STEMI and follow-up evaluation was at the discretion of the treating physicians. In this substudy, classification agreement between follow-up iFR and follow-up FFR was evaluated within groups defined according to follow-up time point after STEMI, i.e., <5days, 5-15days, and16 days. iFR<0.90 and FFR0.80 were considered hemodynamically significant.RESULTS: Among 120 patients with 157 non-culprit stenoses, follow-up iFR and FFR was available in 112 patients with 146 non-culprit stenoses. Median follow-up interval was 16 days (IQR 5-32 days). The overall classification agreement was 84%. With follow-up<5days after STEMI, there was classification agreement between iFR and FFR was in 27 of 35 (77%) non-culprit stenoses. With follow-up 5-15 after STEMI, there was classification agreement in 33 of 38 (86%) non-culprit stenoses. With follow-up 16 days after STEMI, there was classification agreement in 63 of 73 (86%) non-culprit stenoses. The observed differences in these proportions over time after STEMI were not statistically significant (<5versus5days, p¼0.19).CONCLUSION: Overall, classification agreement between iFR and FFR in the assessment of non-culprit lesions after STEMI was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between follow-up iFR and follow-up FFR, although the observed differences were not statistically significant.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
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Thim, Troels
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Götberg, Matthia ...
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Fröbert, Ole, 19 ...
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Nijveldt, Robin
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van Royen, Niels
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Baptista, Sergio
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Koul, Sasha
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Kellerth, Thomas
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Botker, Hans Eri ...
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Christiansen, Ev ...
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Jakobsen, Lars
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Kristensen, Stee ...
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Maeng, Michael
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