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Nonculprit Stenosis...
Nonculprit Stenosis Evaluation Using Instantaneous Wave-Free Ratio in Patients With ST-Segment Elevation Myocardial Infarction
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- Thim, Troels (författare)
- Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
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- Götberg, Matthias (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital
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- Fröbert, Ole, 1964- (författare)
- Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology
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- Nijveldt, Robin (författare)
- Department of Cardiology, VU University Medical Center, Amsterdam, the Netherlands,Amsterdam UMC - Vrije Universiteit Amsterdam
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- van Royen, Niels (författare)
- Department of Cardiology, VU University Medical Center, Amsterdam, the Netherlands,Amsterdam UMC - Vrije Universiteit Amsterdam
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- Baptista, Sergio Bravo (författare)
- Cardiology Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal,Hospital Professor Doutor Fernando Fonseca
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- Koul, Sasha (författare)
- Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital
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- Kellerth, Thomas (författare)
- Örebro University
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- Bøtker, Hans Erik (författare)
- Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
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- Terkelsen, Christian Juhl (författare)
- Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
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- Christiansen, Evald Høj (författare)
- Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
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- Jakobsen, Lars (författare)
- Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
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- Kristensen, Steen Dalby (författare)
- Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
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- Maeng, Michael (författare)
- Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
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(creator_code:org_t)
- New York, USA : Elsevier, 2017
- 2017
- Engelska.
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Ingår i: JACC. - New York, USA : Elsevier. - 1936-8798 .- 1876-7605. ; 10:24, s. 2528-2535
- Relaterad länk:
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https://doi.org/10.1...
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- OBJECTIVES: The aim of this study was to examine the level of agreement between acute instantaneous wave-free ratio (iFR) measured across nonculprit stenoses in patients with ST-segment elevation myocardial infarction (STEMI) and iFR measured at a staged follow-up procedure.BACKGROUND: Acute full revascularization of nonculprit stenoses in STEMI is debated and currently guided by angiography. Acute functional assessment of nonculprit stenoses may be considered.METHODS: Immediately after successful primary culprit intervention for STEMI, nonculprit coronary stenoses were evaluated with iFR and left untreated. Follow-up evaluation with iFR was performed at a later stage. iFR <0.90 was considered hemodynamically significant.RESULTS: One hundred twenty patients with 157 nonculprit lesions were included. Median acute iFR was 0.89 (interquartile range: 0.82 to 0.94; n = 156), and median follow-up iFR was 0.91 (interquartile range [IQR]: 0.86 to 0.96; n = 147). Classification agreement was 78% between acute and follow-up iFR. The negative predictive value of acute iFR was 89%. Median time from acute to follow-up evaluation was 16 days (IQR: 5 to 32 days). With follow-up within 5 days after STEMI, no difference was observed between acute and follow-up iFR, and classification agreement was 89%. With follow-up ≥16 days after STEMI, acute iFR was lower than follow-up iFR, and classification agreement was 70%.CONCLUSIONS: Acute iFR evaluation appeared valid for ruling out significant nonculprit stenoses in patients with STEMI undergoing primary percutaneous coronary intervention. The time interval from acute to follow-up iFR influenced classification agreement, suggesting that inherent physiological disarrangements during STEMI may contribute to classification disagreement.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Complete primary revascularization
- FFR
- full revascularization
- iFR
- primary PCI
- complete primary revascularization
- FFR
- full revascularization
- iFR
- primary PCI
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Thim, Troels
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Götberg, Matthia ...
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Fröbert, Ole, 19 ...
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Nijveldt, Robin
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van Royen, Niels
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Baptista, Sergio ...
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Koul, Sasha
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Kellerth, Thomas
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Bøtker, Hans Eri ...
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Terkelsen, Chris ...
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Christiansen, Ev ...
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Jakobsen, Lars
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Kristensen, Stee ...
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Maeng, Michael
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