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  • Thim, TroelsDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark (författare)

Nonculprit Stenosis Evaluation Using Instantaneous Wave-Free Ratio in Patients With ST-Segment Elevation Myocardial Infarction

  • Artikel/kapitelEngelska2017

Förlag, utgivningsår, omfång ...

  • New York, USA :Elsevier,2017
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:oru-63019
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-63019URI
  • https://doi.org/10.1016/j.jcin.2017.07.021DOI
  • https://lup.lub.lu.se/record/c7039c53-24d0-4bda-8a9e-2ec6e44d8bb4URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Funding Agencies:Volcano Europe BVBA/SPRLNetherlands Organisation for Health Research and Development 90714544 
  • OBJECTIVES: The aim of this study was to examine the level of agreement between acute instantaneous wave-free ratio (iFR) measured across nonculprit stenoses in patients with ST-segment elevation myocardial infarction (STEMI) and iFR measured at a staged follow-up procedure.BACKGROUND: Acute full revascularization of nonculprit stenoses in STEMI is debated and currently guided by angiography. Acute functional assessment of nonculprit stenoses may be considered.METHODS: Immediately after successful primary culprit intervention for STEMI, nonculprit coronary stenoses were evaluated with iFR and left untreated. Follow-up evaluation with iFR was performed at a later stage. iFR <0.90 was considered hemodynamically significant.RESULTS: One hundred twenty patients with 157 nonculprit lesions were included. Median acute iFR was 0.89 (interquartile range: 0.82 to 0.94; n = 156), and median follow-up iFR was 0.91 (interquartile range [IQR]: 0.86 to 0.96; n = 147). Classification agreement was 78% between acute and follow-up iFR. The negative predictive value of acute iFR was 89%. Median time from acute to follow-up evaluation was 16 days (IQR: 5 to 32 days). With follow-up within 5 days after STEMI, no difference was observed between acute and follow-up iFR, and classification agreement was 89%. With follow-up ≥16 days after STEMI, acute iFR was lower than follow-up iFR, and classification agreement was 70%.CONCLUSIONS: Acute iFR evaluation appeared valid for ruling out significant nonculprit stenoses in patients with STEMI undergoing primary percutaneous coronary intervention. The time interval from acute to follow-up iFR influenced classification agreement, suggesting that inherent physiological disarrangements during STEMI may contribute to classification disagreement.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Götberg, MatthiasLund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital(Swepub:lu)kard-mgo (författare)
  • Fröbert, Ole,1964-Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology(Swepub:oru)oft (författare)
  • Nijveldt, RobinDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands,Amsterdam UMC - Vrije Universiteit Amsterdam (författare)
  • van Royen, NielsDepartment of Cardiology, VU University Medical Center, Amsterdam, the Netherlands,Amsterdam UMC - Vrije Universiteit Amsterdam (författare)
  • Baptista, Sergio BravoCardiology Department, Hospital Prof. Doutor Fernando Fonseca, Amadora, Portugal,Hospital Professor Doutor Fernando Fonseca (författare)
  • Koul, SashaLund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-sku (författare)
  • Kellerth, ThomasÖrebro University (författare)
  • Bøtker, Hans ErikDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark (författare)
  • Terkelsen, Christian JuhlDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark (författare)
  • Christiansen, Evald HøjDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark (författare)
  • Jakobsen, LarsDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark (författare)
  • Kristensen, Steen DalbyDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark (författare)
  • Maeng, MichaelDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark (författare)
  • Department of Cardiology, Aarhus University Hospital, Aarhus, DenmarkKardiologi (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:JACCNew York, USA : Elsevier10:24, s. 2528-25351936-87981876-7605

Internetlänk

Hitta via bibliotek

  • JACC (Sök värdpublikationen i LIBRIS)

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