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Sökning: id:"swepub:oai:DiVA.org:oru-65015" > Catheter ablation f...

  • Björkenheim, Anna,1980-Örebro universitet,Institutionen för medicinska vetenskaper (författare)

Catheter ablation for atrial fibrillation : effects on rhythm, symptoms and health-related quality of life

  • BokEngelska2018

Förlag, utgivningsår, omfång ...

  • Örebro :Örebro University,2018
  • 92 s.
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:oru-65015
  • ISBN:9789175292373
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-65015URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:vet swepub-contenttype
  • Ämneskategori:dok swepub-publicationtype

Serie

  • Örebro Studies in Medicine,1652-4063 ;175

Anmärkningar

  • Background: AF ablation is an increasingly used treatment in patients with AF to improve patient-reported outcomes (PROs). Atrioventricular junction ablation (AVJA) is a palliative treatment option in therapy refractory AF that improves PROs but renders the patient pacemaker dependent.Aims: To evaluate rhythm control and PROs before and up to two years after AF ablation. To analyze the long-term incidence of and predictors of hospitalization for HF and all-cause mortality in patients who underwent AVJA and right ventricular pacing.Methods and Results: Fifty-four patients underwent AF ablation and both continuous rhythm monitoring via an implantable loop recorder (ILR) and intermittent rhythm monitoring three, six, 12 and 24 months after ablation. 76 % of patients had at least one AF recurrence, of whom 24 % were only detected by ILR. One third of symptom recordings did not show AF. The AF-specific AF6 scores, physician-assessed EHRA symptom class and both SF-36 summary scores all improved significantly from before to two years after ablation. There was a weak correlation between the change in AF6 scores and EHRA class from before to six and 12 months but not to 24 months after ablation. Responders to ablation (AF burden < 0.5 %), reached age- and sex-matched norms in all SF-36 domains, but non-responders only in social functioning and MCS. All AF6 scores showed at least moderate improvement in both responders and non-responders. Higher AF burden was independently associated with poorer PCS and AF6 scores. In 162 patients who underwent AVJA, hospitalization for HF occurred in 20 % of patients (two-year cumula-tive incidence 9.1 %) and 22 % died (two-year cumulative incidence 5.2 %) during a median follow-up of five years. QRS ≥ 120 ms and left atrial diame-ter were independent predictors of hospitalization for HF, and hypertension and previous HF of death.Conclusions: Continuous rhythm monitoring was superior to intermittent monitoring. The AF-specific AF6 was more sensitive to changes related to AF burden after AF ablation than both EHRA class and the SF-36. The long-term hospitalization rate for HF and all-cause mortality was low after AVJA.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Poçi, Dritan,Medicine doktor,1969-Örebro universitet,Institutionen för medicinska vetenskaper(Swepub:oru)dnpi (preses)
  • Lane, Deirdre,ProfessorInstitute of Cardiovascular Sciences, University of Birmingham (opponent)
  • Örebro universitetInstitutionen för medicinska vetenskaper (creator_code:org_t)

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