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- Lamichhane, SantoshTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, Finland (author)
Gut metabolome meets microbiome : A methodological perspective to understand the relationship between host and microbe
- Article/chapterEnglish2018
Publisher, publication year, extent ...
- Academic Press,2018
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:oru-66868
- https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-66868URI
- https://doi.org/10.1016/j.ymeth.2018.04.029DOI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Funding Agencies:Juvenile Diabetes Research Foundation 2-SRA-2014-159-Q-R Academy of Finland 292568
- It is well established that gut microbes and their metabolic products regulate host metabolism. The interactions between the host and its gut microbiota are highly dynamic and complex. In this review we present and discuss the metabolomic strategies to study the gut microbial ecosystem. We highlight the metabolic profiling approaches to study faecal samples aimed at deciphering the metabolic product derived from gut microbiota. We also discuss how metabolomics data can be integrated with metagenomics data derived from gut microbiota and how such approaches may lead to better understanding of the microbial functions. Finally, the emerging approaches of genome-scale metabolic modelling to study microbial co-metabolism and host-microbe interactions are highlighted.
Subject headings and genre
- NATURVETENSKAP Biologi Mikrobiologi hsv//swe
- NATURAL SCIENCES Biological Sciences Microbiology hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Cell- och molekylärbiologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Cell and Molecular Biology hsv//eng
- Faecal metabolites
- Genome-scale metabolic models
- Gut microbiota
- Metabolomics
- Microbiome
Added entries (persons, corporate bodies, meetings, titles ...)
- Sen, ParthoTurku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, Finland (author)
- Dickens, Alex M.Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, Finland (author)
- Oresic, Matej,1967-Örebro universitet,Institutionen för medicinska vetenskaper,Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, Finland(Swepub:oru)moc (author)
- Bertram, Hanne ChristineDepartment of Food Science, Aarhus University, Aarslev, Denmark (author)
- Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, FinlandInstitutionen för medicinska vetenskaper (creator_code:org_t)
Related titles
- In:Methods: Academic Press149, s. 3-121046-20231095-9130
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