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  • Tagliaferri, LucaFondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy (author)

ENT COBRA ONTOLOGY : the covariates classification system proposed by the Head & Neck and Skin GEC-ESTRO Working Group for interdisciplinary standardized data collection in head and neck patient cohorts treated with interventional radiotherapy (brachytherapy)

  • Article/chapterEnglish2018

Publisher, publication year, extent ...

  • Termedia Publishing,2018
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:oru-68257
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-68257URI
  • https://doi.org/10.5114/jcb.2018.76982DOI

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  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:for swepub-publicationtype

Notes

  • Purpose: Clinical data collecting is expensive in terms of time and human resources. Data can be collected in different ways; therefore, performing multicentric research based on previously stored data is often difficult. The primary objective of the ENT COBRA (COnsortium for BRachytherapy data Analysis) ontology is to define a specific terminological system to standardized data collection for head and neck (H&N) cancer patients treated with interventional radiotherapy.Material and methods: ENT-COBRA is a consortium for standardized data collection for H&N patients treated with interventional radiotherapy. It is linked to H&N and Skin GEC-ESTRO Working Group and includes 11 centers from 6 countries. Its ontology was firstly defined by a multicentric working group, then evaluated by the consortium followed by a multi-professional technical commission involving a mathematician, an engineer, a physician with experience in data storage, a programmer, and a software expert.Results: Two hundred and forty variables were defined on 13 input forms. There are 3 levels, each offering a specific type of analysis: 1. Registry level (epidemiology analysis); 2. Procedures level (standard oncology analysis); 3. Research level (radiomics analysis). The ontology was approved by the consortium and technical commission; an ad-hoc software architecture ("broker") remaps the data present in already existing storage systems of the various centers according to the shared terminology system. The first data sharing was successfully performed using COBRA software and the ENT COBRA Ontology, automatically collecting data directly from 3 different hospital databases (Lubeck, Navarra, and Rome) in November 2017.Conclusions: The COBRA Ontology is a good response to the multi-dimensional criticalities of data collection, retrieval, and usability. It allows to create a software for large multicentric databases with implementation of specific remapping functions wherever necessary. This approach is well-received by all involved parties, primarily because it does not change a single center's storing technologies, procedures, and habits.

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  • Budrukkar, AshwiniTata Memorial Centre, Mumbai, India (author)
  • Lenkowicz, JacopoFondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy (author)
  • Cambeiro, MauricioClìnica Universidad de Navarra, Navarra, Spain (author)
  • Bussu, FrancescoHead of the Otolaryngology Division, Azienda Ospedaliero-Universitaria di Sassari, Italy (author)
  • Guinot, Jose LuisDepartment of Radiation Oncology, Fundacion Instituto Valenciano de Oncologia, Valencia, Spain (author)
  • Hildebrandt, GuidoUniversity Hospital Radiotherapy Department, University of Rostock, Rostock, Germany (author)
  • Johansson, Bengt,1958-Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Oncology(Swepub:oru)btjn (author)
  • Meyer, Jens E.Head & Neck Surgery Department, AK St. George Hospital, Hamburg, Germany (author)
  • Niehoff, PeterDepartment of Radiotherapy, Sana Hospital Offenbach, Offenbach, Germany (author)
  • Rovirosa, AngelesHospital Clinic I Universitaria, Barcelona, Spain (author)
  • Takacsi-Nagy, ZoltanNational Cancer Institute, Budapest, Hungary (author)
  • Boldrini, LucaFondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy (author)
  • Dinapoli, NicolaFondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy (author)
  • Lanzotti, VitoFondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy (author)
  • Damiani, AndreaFondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy (author)
  • Gatta, RobertoFondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy (author)
  • Fionda, BrunoFondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy (author)
  • Lancellotta, ValentinaRadiation Oncology Section, Department of Surgical and Biomedical Science, University of Perugia and Perugia General Hospital, Perugia, Italy (author)
  • Soror, TamerInterdisciplinary Brachytherapy Unit, University of Lübeck – University Hospital S-H, Campus Lübeck, Germany (author)
  • Monge, Rafael MartinezClìnica Universidad de Navarra, Navarra, Spain (author)
  • Valentini, VincenzoFondazione Policlinico A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy (author)
  • Kovacs, GyoergyInterdisciplinary Brachytherapy Unit, University of Lübeck – University Hospital S-H, Campus Lübeck, Germany (author)
  • Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, ItalyTata Memorial Centre, Mumbai, India (creator_code:org_t)

Related titles

  • In:Journal of Contemporary Brachytherapy: Termedia Publishing10:3, s. 260-2661689-832X2081-2841

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