Does zero atrial fibrillation burden after atrial fibrillation ablation mean that patients are free of symptoms?

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: WFRF:(Poçi Dritan 1969 ) > Does zero atrial fi...

Björkenheim, Anna,1980-Department of Cardiology, Örebro University Hospital, Örebro, Sweden (författare)

Does zero atrial fibrillation burden after atrial fibrillation ablation mean that patients are free of symptoms?

Artikel/kapitelEngelska2017

Förlag, utgivningsår, omfång ...

2017-06-20
Oxford University Press,2017
printrdacarrier

Nummerbeteckningar

LIBRIS-ID:oai:DiVA.org:oru-69420
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-69420URI
https://doi.org/10.1093/ehjci/eux157.001DOI

Kompletterande språkuppgifter

Språk:engelska
Sammanfattning på:engelska

Ingår i deldatabas

SwePubSwePub

Klassifikation

Ämneskategori:ref swepub-contenttype
Ämneskategori:art swepub-publicationtype

Anmärkningar

Introduction: Success of atrial fibrillation (AF) ablation is usually defined as freedom of AF, although symptomatic relief often is what the patient’s desire. After ablation the proportion of ‘silent’ AF increases and success based on symptomatic AF recurrence may be overestimated.Purpose: To investigate the symptomatology of patients who are truly free of AF after ablation.Methods: In 57 patients the symptomatology after AF ablation was assessed as perceived by the patient using a validated AF-specific symptom questionnaire (AF6) and the overall treatment effect (OTE), and as classified by the physician using the EHRA score, at baseline, 6, 12 and 24 months. The cardiac rhythm was continuously monitored by an implantable loop recorder throughout the 2-year follow-up.Results: At 6, 12 and 24 months 14 (26%), 23 (43%) and 23 (43%) patients had an AF burden 0% during the past 6 months, and 13 of them had an AF burden 0% during the entire 2 year follow-up. All patients reported ‘OTE better’ at all time-points. All patients were also classified into EHRA I at 6 months. Being completely free of AF for six months periods did not mean complete freedom of symptoms, but the median AF6 sum score was consistently low with a narrowing IQR over time, 0 (IQR 0-27), 0.5 (IQR 0-7) and 0 (IQR 0-11) at 6, 12 and 24 months. At 6 months 8/14 patients (57%) scored AF6=0, the others 6, 11, 26, 28, 30 and 46 points. At 12 months 13/23 patients (56%) scored AF6=0, the others 1,1,3,3,5,7,7,7,14 and 22 points. At 24 months 12/23 (52%) patients scored AF6=0, the others 1, 1, 2, 4, 9, 11, 17, 20, 24, 32 and 42 points. Among the AF6 items, ‘worry/anxiety due to AF’ was the most common, while ‘tiredness due to AF’ was the highest scoring item. In the patients with AF burden 0% during the entire 2-year follow-up all patients were improved in OTE and all patients were classified into EHRA class I at all times after ablation and the median AF6 sum score was 4 (IQR0-28), 0.5 (IQR 0-8) and 1 (0-5) at 6, 12 and 24 months after ablation.Conclusions: Sudden elimination of AF by ablation does not automatically eliminate all symptoms that the patients associated with AF, but all patients felt better and were classified in EHRA class I at all time-points. Less than a half of the patients at any time-point scored some symptoms, but the symptoms gradually decreased over time, especially between 6 and 12 months.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

Brandes, A.Department of Cardiology, Odense University Hospital, Odense, Denmark (författare)
Magnuson, A.Örebro University Hospital, Clinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden (författare)
Chemnitz, A.Department of Cardiology, Odense University Hospital, Odense, Denmark (författare)
Svedberg, L.Department of Cardiology, Örebro University Hospital, Örebro, Sweden (författare)
Edvardsson, N.Sahlgrenska Academy at Sahlgrenska University Hospital, Göteborg, Sweden (författare)
Poçi, Dritan,1969-Department of Cardiology, Örebro University Hospital, Örebro, Sweden(Swepub:oru)dnpi (författare)
Department of Cardiology, Örebro University Hospital, Örebro, SwedenDepartment of Cardiology, Odense University Hospital, Odense, Denmark (creator_code:org_t)

Sammanhörande titlar

Ingår i:Europace, Supplements: Oxford University Press19:Duppl. 3, s. iii264-iii2641099-60441749-365X
Ingår i:EP Europace: Oxford University Press19:Duppl. 3, s. iii264-iii2641099-51291532-2092

Internetlänk

Hitta via bibliotek

Europace, Supplements (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...: Björkenheim, Ann ...; Brandes, A.; Magnuson, A.; Chemnitz, A.; Svedberg, L.; Edvardsson, N.; visa fler...; Poçi, Dritan, 19 ...; visa färre...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Kardiologi

Artiklar i publikationen: Europace, Supple ...; EP Europace

Av lärosätet: Örebro universitet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se