A Cross-Sectional Analysis of Body Composition Among Healthy Elderly From the European NU-AGE Study: Sex and Country Specific Features

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A Cross-Sectional Analysis of Body Composition Among Healthy Elderly From the European NU-AGE Study : Sex and Country Specific Features

Santoro, Aurelia (författare): Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy; C.I.G. Interdepartmental Centre “L. Galvani”, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Bazzocchi, Alberto (författare): IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

Guidarelli, Giulia (författare): Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy

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Ostan, Rita (författare): Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy; C.I.G. Interdepartmental Centre “L. Galvani”, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Giampieri, Enrico (författare): Department of Physics, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Mercatelli, Daniele (författare): IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

Scurti, Maria (författare): Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy; Institute of Neurological Sciences (IRCCS), Bologna, Italy

Berendsen, Agnes (författare): Division of Human Nutrition and Health, Wageningen University and Research, Wageningen, Netherlands

Surala, Olga (författare): Department of Human Nutrition, Warsaw University of Life Sciences - SGGW, Warsaw, Poland

Jennings, Amy (författare): Norwich Medical School, University of East Anglia, Norwich, United Kingdom

Meunier, Nathalie (författare): CHU Clermont-Ferrand, Clermont-Ferrand, France

Caumon, Elodie (författare): CHU Clermont-Ferrand, Clermont-Ferrand, France

Gillings, Rachel (författare): Norwich Medical School, University of East Anglia, Norwich, United Kingdom

Kadi, Fawzi, 1970- (författare): Örebro universitet,Institutionen för hälsovetenskaper

Capel, Frederic (författare): Unité de Nutrition Humaine, INRA, Université Clermont Auvergne, Clermont-Ferrand, France

Cashman, Kevin D. (författare): Cork Centre for Vitamin D and Nutrition Research, School of Food and Nutritional Sciences, University College Cork, Cork, Ireland

Pietruszka, Barbara (författare): Department of Human Nutrition, Warsaw University of Life Sciences - SGGW, Warsaw, Poland

Feskens, Edith J. M. (författare): Division of Human Nutrition and Health, Wageningen University and Research, Wageningen, Netherlands

De Groot, Lisette C. P. G. M. (författare): Division of Human Nutrition and Health, Wageningen University and Research, Wageningen, Netherlands

Battista, Giuseppe (författare): Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Salvioli, Stefano (författare): Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy; C.I.G. Interdepartmental Centre “L. Galvani”, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Franceschi, Claudio (författare): Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy; Institute of Neurological Sciences (IRCCS), Bologna, Italy

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Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy; CI.G. Interdepartmental Centre “L. Galvani”, Alma Mater Studiorum, University of Bologna, Bologna, Italy IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy (creator_code:org_t)

2018-11-30
2018
Engelska.
Ingår i: Frontiers in Physiology. - : Frontiers Media S.A.. - 1664-042X. ; 9

Relaterad länk:: https://doi.org/10.3...; visa fler...; https://www.frontier...; https://urn.kb.se/re...; https://doi.org/10.3...; visa färre...

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Body composition (BC) is an emerging important factor for the characterization of metabolic status. The assessment of BC has been studied in various populations and diseases such as obesity, diabetes, endocrine diseases as well as physiological and paraphysiological conditions such as growth and aging processes, and physical training. A gold standard technique for the assessment of human BC at molecular level is represented by dual-energy X-ray absorptiometry (DXA), which is able to precisely assess the body mass (and areal bone mineral density-aBMD) on a regional and whole-body basis. For the first time, within the framework of the NU-AGE project, BC has been assessed by means of a whole-body DXA scan in 1121 sex-balanced free-living, apparently healthy older adults aged 65-79 years enrolled in 5 European countries (Italy, France, United Kingdom, Netherlands, and Poland). The aim of this analysis is to provide a complete profile of BC in healthy elderly participants from five European countries and to investigate country- and sex-related differences by state-of-the-art DXA technology. To compare BC data collected in different centers, specific indexes and ratios have been used. Non-parametric statistical tests showed sex-specific significant differences in certain BC parameters. In particular, women have higher fat mass (FM) (Fat/Lean mass ratio: by 67%, p < 2.2e-16) and lower lean mass (Lean Mass index: by -18%, p < 2.2e-16) than men. On the other hand, men have higher android FM than women (Android/gynoid FM ratio: by 56%, p < 2.2e-16). Interesting differences also emerged among countries. Polish elderly have higher FM (Fat/Lean mass ratio: by 52%, p < 2.2e-16) and lower lean mass (Skeletal Mass index: by -23%, p < 2.2e-16) than elderly from the other four countries. At variance, French elderly show lower FM (Fat/Lean mass ratio: by -34%, p < 2.2e-16) and higher lean mass (Skeletal Mass index: by 18%, p < 2.2e-16). Moreover, five BC profiles in women and six in men have been identified by a cluster analysis based on BC parameters. Finally, these data can serve as reference for normative average and variability of BC in the elderly populations across Europe.

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A Cross-Sectional Analysis of Body Composition Among Healthy Elderly From the European NU-AGE Study : Sex and Country Specific Features

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