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Informatics and computational strategies for the study of lipids

Yetukuri, Laxman (author)
VTT Technical Research Centre of Finland, Espoo, Finland
Ekroos, Kim (author)
VTT Technical Research Centre of Finland, Espoo, Finland
Vidal-Puig, Antonio (author)
University of Cambridge Department of Clinical Biochemistry, Addenbrooke's Hospital, Hills Road, Cambridge, UK
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Oresic, Matej, 1967- (author)
VTT Technical Research Centre of Finland, Espoo, Finland
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 (creator_code:org_t)
2008
2008
English.
In: Molecular Biosystems. - : Royal Society of Chemistry. - 1742-206X .- 1742-2051. ; 4:2, s. 121-127
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Recent advances in mass spectrometry (MS)-based techniques for lipidomic analysis have empowered us with the tools that afford studies of lipidomes at the systems level. However, these techniques pose a number of challenges for lipidomic raw data processing, lipid informatics, and the interpretation of lipidomic data in the context of lipid function and structure. Integration of lipidomic data with other systemic levels, such as genomic or proteomic, in the context of molecular pathways and biophysical processes provides a basis for the understanding of lipid function at the systems level. The present report, based on the limited literature, is an update on a young but rapidly emerging field of lipid informatics and related pathway reconstruction strategies.

Subject headings

NATURVETENSKAP  -- Biologi -- Bioinformatik och systembiologi (hsv//swe)
NATURAL SCIENCES  -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)

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Yetukuri, Laxman
Ekroos, Kim
Vidal-Puig, Anto ...
Oresic, Matej, 1 ...
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NATURAL SCIENCES
NATURAL SCIENCES
and Biological Scien ...
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Molecular Biosys ...
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Örebro University

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