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Unmet Medical Needs...
Unmet Medical Needs in Ulcerative Colitis : An Expert Group Consensus
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- Danese, Silvio (författare)
- Humanitas Research Hospital, Milan, Italy
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- Allez, Matthieu (författare)
- Department of Gastroenterology and Hepatology, Hôpital Saint-Louis, Paris, France
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- van Bodegraven, Ad A. (författare)
- Zuyderland Medical Center, Sittard and VU University Medical Center, Amsterdam, The Netherlands
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- Dotan, Iris (författare)
- Division of Gastrotenterology, Rabin Medical Center, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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- Gisbert, Javier P. (författare)
- Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IIS-IP), Universidad Autónoma de Madrid, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain
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- Hart, Ailsa (författare)
- IBD Unit, St. Mark’s Hospital, London, United Kingdom
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- Lakatos, Peter L. (författare)
- McGill University, MUHC, Montreal General Hospital, Montreal, QC, Canada; Department of Medicine, Semmelweis University, Budapest, Hungary
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- Magro, Fernando (författare)
- University of Porto and Centro Hospitalar São João, Porto, Portugal
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- Peyrin-Biroulet, Laurent (författare)
- Nancy University Hospital and Université de Lorraine, Nancy, France
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- Schreiber, Stefan (författare)
- University Hospital Schleswig-Holstein, Kiel, Germany
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- Tarabar, Dino (författare)
- Clinic for Gastroenterology and Hepatology, Military Medical Academy, Belgrade, Serbia
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- Vavricka, Stephan (författare)
- Division of Gastroenterology, Stadtspital Triemli, Zurich, Switzerland
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- Halfvarson, Jonas, 1970- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper
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- Vermeire, Séverine (författare)
- University Hospital Leuven, Leuven, Belgium
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(creator_code:org_t)
- 2019-02-06
- 2019
- Engelska.
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Ingår i: Digestive Diseases. - : S. Karger. - 0257-2753 .- 1421-9875. ; 37:4, s. 266-283
- Relaterad länk:
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https://www.karger.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- BACKGROUND: The authors aimed to conduct an extensive literature review and consensus meeting to identify unmet needs in ulcerative colitis (UC) and ways to overcome them. UC is a relapsing and remitting inflammatory bowel disease with varied, and changing, incidence rates worldwide. UC has an unpredictable disease course and is associated with a high health economic burden. During 2016 and 2017, a panel of experts was convened to identify, discuss and address areas of unmet need in UC.METHODS: PubMed and Cochrane Library databases were searched for relevant articles describing studies performed in patients with UC. These findings were used to generate a set of statements relating to unmet needs in UC. Consensus on these statements was then sought from a panel of 9 expert gastroenterologists using a modified Delphi review process that consisted of anonymous surveys followed by live meetings.RESULTS: In 2 literature reviews, over 5,000 unique records were identified and a total of 138 articles were fully reviewed. These were used to consider 26 areas of unmet need, which were explored in 2 face-to-face meetings, in which the statements were debated and amended, resulting in consensus on 30 final statements. The unmet needs identified were categorised into 7 areas: impact of UC on patients' daily life; importance of early diagnosis and treatment; drawbacks of existing treatments; urgent need for new treatments; and disease-, practice- or patient-focused unmet needs.CONCLUSIONS: These expert group meetings found a number of areas of unmet needs in UC, which is an important first step in tackling them in the future. Future research and development should be focused in these areas for the management of patients with UC.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Nyckelord
- Consensus panel
- Delphi process
- Systematic literature review
- Ulcerative colitis
- Unmet needs
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- Av författaren/redakt...
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Danese, Silvio
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Allez, Matthieu
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van Bodegraven, ...
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Dotan, Iris
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Gisbert, Javier ...
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Hart, Ailsa
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Lakatos, Peter L ...
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Magro, Fernando
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Peyrin-Biroulet, ...
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Schreiber, Stefa ...
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Tarabar, Dino
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Vavricka, Stepha ...
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Halfvarson, Jona ...
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Vermeire, Séveri ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Gastroenterologi
- Artiklar i publikationen
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Digestive Diseas ...
- Av lärosätet
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Örebro universitet