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Sökning: WFRF:(Tsolaki Magda) > Bos Isabelle > The frequency and i...

  • Bos, IsabelleDepartment of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, Netherlands (författare)

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

  • Artikel/kapitelEngelska2017

Förlag, utgivningsår, omfång ...

  • Elsevier,2017
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:oru-74047
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-74047URI
  • https://doi.org/10.1016/j.neurobiolaging.2017.03.034DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:136232937URI
  • https://lup.lub.lu.se/record/f9eda6d8-d679-4d81-b560-6c3801a70540URI
  • https://gup.ub.gu.se/publication/254306URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

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  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • We investigated whether dementia risk factors were associated with prodromal Alzheimer's disease (AD) according to the International Working Group-2 and National Institute of Aging-Alzheimer's Association criteria, and with cognitive decline. A total of 1394 subjects with mild cognitive impairment from 14 different studies were classified according to these research criteria, based on cognitive performance and biomarkers. We compared the frequency of 10 risk factors between the subgroups, and used Cox-regression to examine the effect of risk factors on cognitive decline. Depression, obesity, and hypercholesterolemia occurred more often in individuals with low-AD-likelihood, compared with those with a high-AD-likelihood. Only alcohol use increased the risk of cognitive decline, regardless of AD pathology. These results suggest that traditional risk factors for AD are not associated with prodromal AD or with progression to dementia, among subjects with mild cognitive impairment. Future studies should validate these findings and determine whether risk factors might be of influence at an earlier stage (i.e., preclinical) of AD.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Vos, Stephanie J.Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, Netherlands (författare)
  • Frölich, LutzDepartment of Geriatric Psychiatry, Zentralinstitut für Seelische Gesundheit, University of Heidelberg, Mannheim, Germany (författare)
  • Kornhuber, JohannesDepartment of Psychiatry and Psychotherapy, Friedrich-Alexander University of Erlangen-Nürnberg, Erlangen, Germany (författare)
  • Wiltfang, JensDepartment of Psychiatry and Psychotherapy, University Medical Center (UMC), Georg-August-University, Göttingen, Germany (författare)
  • Maier, WolfgangDepartment of Psychiatry and Psychotherapy, University of Bonn, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany (författare)
  • Peters, OliverDepartment of Psychiatry and Psychotherapy, Charité Berlin, Berlin, Germany,Charité - University Medicine Berlin (författare)
  • Rüther, EckhartDepartment of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany (författare)
  • Engelborghs, SebastiaanDepartment of Neurology and Memory Clinic, Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken, Antwerp, Belgium; Reference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium (författare)
  • Niemantsverdriet, EllisReference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium (författare)
  • De Roeck, Ellen ElisaReference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium; Department of Clinical and Lifespan Psychology, Vrije Universiteit Brussel, Brussels, Belgium,Vrije Universiteit Brussel (VUB) (författare)
  • Tsolaki, Magda3rd Department of Neurology, Aristotle University of Thessaloniki, Memory and Dementia Center, “G Papanicolau” General Hospital, Thessaloniki, Greece (författare)
  • Freund-Levi, Yvonne,1956-Karolinska Institute,Karolinska University Hospital(Swepub:oru)yfi (författare)
  • Johannsen, PeterDanish Dementia Research Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark (författare)
  • Vandenberghe, RikDepartment of Neurology, University of Hospital Leuven, Leuven, Belgium; Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Belgium,Catholic University of Leuven (författare)
  • Lleó, AlbertoHospital de la Santa Creu i Sant Pau, Barcelona, Spain (författare)
  • Alcolea, DanielHospital de la Santa Creu i Sant Pau, Barcelona, Spain (författare)
  • Frisoni, Giovanni B.Geneva Neuroscience Center, University Hospital and University of Geneva, Geneva, Switzerland; IRCCS San Giovanni di Dio Fatebenefratelli, Brescia, Italy (författare)
  • Galluzzi, SamanthaIRCCS San Giovanni di Dio Fatebenefratelli, Brescia, Italy,Centro San Giovanni di Dio Fatebenefratelli (författare)
  • Nobili, FlavioClinical Neurology, Department of Neurosciences (DINOGMI), University of Genoa and IRCCS AOU San Martino-IST, Genoa, Italy,Ospedale Policlinico San Martino (författare)
  • Morbelli, SilviaNuclear Medicine, Department of Health Science (DISSAL), University of Genoa IRCCS AOU San Martino-IST, Genoa, Italy,Ospedale Policlinico San Martino (författare)
  • Drzezga, AlexanderDepartment of Nuclear Medicine, University of Cologne, Cologne, Germany (författare)
  • Didic, MiraAP-HM Hôpitaux de la Timone, Service de Neurologie et Neuropsychologie, Marseille, France; Aix-Marseille Université, INSERM, Institut de Neurosciences des Systèmes, Marseille, France,La Timone University Hospital (författare)
  • van Berckel, Bart N.Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands,Amsterdam UMC - Vrije Universiteit Amsterdam (författare)
  • Salmon, EricDepartment of Neurology and Memory Clinic, CHU Liège, Liège, Belgium; GIGA-CRC in vivo Imaging, University of Liège, Liège, Belgium,University of Liège Hospital (författare)
  • Bastin, ChristineGIGA-CRC in vivo Imaging, University of Liège, Liège, Belgium (författare)
  • Dauby, SoleneDepartment of Neurology and Memory Clinic, CHU Liège, Liège, Belgium,University of Liège Hospital (författare)
  • Santana, IsabelDepartment of Neurology and Memory Clinic, CHU Liège, Liège, Belgium,University of Liège Hospital (författare)
  • Baldeiras, InêsCenter for Neuroscience and Cell Biology, Faculty of Medicine, Department of Neurology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal,University Hospital of Coimbra (författare)
  • de Mendonça, AlexandreInstitute of Molecular Medicine and Faculty of Medicine, University of Lisbon, Portugal (författare)
  • Silva, DinaInstitute of Molecular Medicine and Faculty of Medicine, University of Lisbon, Portugal (författare)
  • Wallin, Anders,1950Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry(Swepub:gu)xwaand (författare)
  • Nordlund, Arto,1962Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry(Swepub:gu)xnorar (författare)
  • Coloma, Preciosa M.Real World Data Science (RWD-S) Neuroscience and Established Products, F. Hoffmann-La Roche Ltd. Pharmaceuticals Division, Basel, Switzerland (författare)
  • Wientzek, AngelikaPDB RWD (Real World Data) Team, Roche Products Limited, Welwyn Garden City, UK; Epidemiologische Beratung und Literatur-Recherche “conepi”, Herrsching, Germany (författare)
  • Alexander, MyriamPDB RWD (Real World Data) Team, Roche Products Limited, Welwyn Garden City, UK (författare)
  • Novak, Gerald P.Janssen Pharmaceutical Research and Development, Titusville, NJ, USA (författare)
  • Gordon, Mark ForrestBoehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT, USA (författare)
  • Wallin, Åsa K.Lund University,Lunds universitet,Klinisk minnesforskning,Forskargrupper vid Lunds universitet,Clinical Memory Research,Lund University Research Groups(Swepub:lu)med-was (författare)
  • Hampel, HaraldSorbonne Universités, Université Pierre et Marie Curie, Paris 06, AXA Research Fund & UPMC Chair, Institut de la Mémoire et de la Maladie d’Alzheimer (IM2A), Paris, France; Institut du Cerveau et de la Moelle épinière (ICM), Département de Neurologie, Hôpital de la Pitié-Salpétrière, Paris, France (författare)
  • Soininen, HilkkaInstitute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland; Neurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland (författare)
  • Herukka, Sanna-KaisaInstitute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland; Neurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland (författare)
  • Scheltens, PhilipAlzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, Netherlands,Amsterdam UMC - Vrije Universiteit Amsterdam (författare)
  • Verhey, Frans R.Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, Netherlands (författare)
  • Visser, Pieter JelleDepartment of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, Netherlands; Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, Netherlands,Amsterdam UMC - Vrije Universiteit Amsterdam (författare)
  • Alzheimer's Disease Neuroimaging Initiative, the (bidragsgivare)
  • Department of Psychiatry and Neuropsychology, Maastricht University, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht, NetherlandsDepartment of Geriatric Psychiatry, Zentralinstitut für Seelische Gesundheit, University of Heidelberg, Mannheim, Germany (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Neurobiology of Aging: Elsevier56, s. 33-400197-45801558-1497

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