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Clinical and angiog...
Clinical and angiographic outcomes of bioabsorbable vs. permanent polymer drug-eluting stents in Sweden : a report from the Swedish Coronary and Angioplasty Registry (SCAAR)
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- Buccheri, Sergio (författare)
- Uppsala University,Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)
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- James, Stefan, 1964- (författare)
- Uppsala University,Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)
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- Lindholm, Daniel, 1982- (författare)
- Uppsala University,Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)
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- Fröbert, Ole, 1964- (författare)
- Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Cardiology,Orebro Univ, Fac Hlth, Dept Cardiol, S-70185 Orebro, Sweden
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- Olivecrona, Göran K. (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Persson, Jonas (författare)
- Karolinska Institutet
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- Hambraeus, Kristina (författare)
- Department of Cardiology, Falu Lasarett, Falun, Sweden,Falu Lasarett, Dept Cardiol, Falun, Sweden,Falun Central Hospital
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- Witt, Nils (författare)
- Karolinska Institutet,Karolinska Institute
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- Erlinge, David (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Angerås, Oskar (författare)
- Department of Cardiology, Sahlgrenska University Hospital, Göteborg, Sweden,Sahlgrens Univ Hosp, Dept Cardiol, Bruna Straket 16, S-41345 Gothenburg, Sweden
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- Lagerqvist, Bo, 1952- (författare)
- Uppsala University,Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi
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- Sarno, Giovanna (författare)
- Uppsala University,Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi
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(creator_code:org_t)
- 2019-05-11
- 2019
- Engelska.
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Ingår i: European Heart Journal. - : Oxford University Press. - 0195-668X .- 1522-9645. ; 40:31, s. 2607-2615
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http://dx.doi.org/10...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- AIMS: Randomized clinical trials have consistently demonstrated the non-inferiority of bioabsorbable polymer drug-eluting stents (BP-DES) with respect to DES having permanent polymers (PP-DES). To date, the comparative performance of BP- and PP-DES in the real world has not been extensively investigated.METHODS AND RESULTS: From October 2011 to June 2016, we analysed the outcomes associated with newer generation DES use in Sweden. After stratification according to the type of DES received at the index procedure, a total of 16 504 and 79 106 stents were included in the BP- and PP-DES groups, respectively. The Kaplan-Meier estimates for restenosis at 2 years were 1.2% and 1.4% in BP- and PP-DES groups, respectively. Definite stent thrombosis (ST) was low in both groups (0.5% and 0.7% in BP- and PP-DES groups, respectively). The adjusted hazard ratio (HR) for either restenosis or definite ST did not differ between BP- and PP-DES [adjusted HR 0.95, 95% confidence interval (CI) 0.74-1.21; P = 0.670 and adjusted HR 0.79, 95% CI 0.57-1.09; P = 0.151, respectively]. Similarly, there were no differences in the adjusted risk of all-cause death and myocardial infarction (MI) between the two groups (adjusted HR for all-cause death 1.01, 95% CI 0.82-1.25; P = 0.918 and adjusted HR for MI 1.05, 95% CI 0.93-1.19; P = 0.404).CONCLUSION: In a large, nationwide, and unselected cohort of patients, percutaneous coronary intervention with BP-DES implantation was not associated with an incremental clinical benefit over PP-DES use at 2 years follow-up.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Bioabsorbable polymer
- Clinical outcomes
- Drug-eluting stents
- Permanent polymer
- Stent failure
- Bioabsorbable polymer
- Clinical outcomes
- Drug-eluting stents
- Permanent polymer
- Stent failure
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Buccheri, Sergio
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James, Stefan, 1 ...
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Lindholm, Daniel ...
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Fröbert, Ole, 19 ...
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Olivecrona, Göra ...
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Persson, Jonas
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Hambraeus, Krist ...
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Witt, Nils
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Erlinge, David
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Angerås, Oskar
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Lagerqvist, Bo, ...
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Sarno, Giovanna
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visa färre...
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European Heart J ...
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Örebro universitet
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Uppsala universitet
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Lunds universitet
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Karolinska Institutet