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Anorexia Nervosa With Comorbid Severe Depression : A Systematic Scoping Review of Brain Stimulation Treatments

Andersson, Peter (författare)
Karolinska Institutet,Uppsala universitet,Centrum för klinisk forskning Dalarna,Karolinska Inst, Dept Clin Neurosci Psychol, Stockholm, Sweden.,Department of Clinical Neuroscience/Psychology, Karolinska Institute, Stockholm, Sweden; Center for Clinical Research Dalarna, Uppsala University, Falun, Sweden
Jamshidi, Esmail (författare)
Umeå universitet,Psykiatri,Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden,Reg Stockholm, Stockholm Hlth Care Serv, Stockholm, Sweden.;Umeå Univ, Dept Clin Sci Psychiat, Umeå, Sweden.
Ekman, Carl-Johan (författare)
Karolinska Institutet,Reg Stockholm, Stockholm Hlth Care Serv, Stockholm, Sweden.;Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, SE-17176 Stockholm, Sweden.;Karolinska Univ Hosp, Stockholm Hlth Care Serv, Reg Stockholm, SE-17176 Stockholm, Sweden.
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Tedroff, Kristina (författare)
Karolinska Institutet,Karolinska Univ Hosp, Stockholm Hlth Care Serv, Reg Stockholm, SE-17176 Stockholm, Sweden.
Björkander, Jonnie (författare)
Reg Stockholm, Stockholm Hlth Care Serv, Stockholm, Sweden.,Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden
Sjögren, Magnus (författare)
Umeå universitet,Psykiatri,Umeå Univ, Dept Clin Sci Psychiat, Umeå, Sweden.
Lundberg, Johan (författare)
Karolinska Institutet,Reg Stockholm, Stockholm Hlth Care Serv, Stockholm, Sweden.;Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, SE-17176 Stockholm, Sweden.;Karolinska Univ Hosp, Stockholm Hlth Care Serv, Reg Stockholm, SE-17176 Stockholm, Sweden.
Jokinen, Jussi (författare)
Karolinska Institutet,Umeå universitet,Psykiatri,Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Karolinska University Hospital, Region Stockholm, Stockholm, Sweden; Stockholm Health Care Services, Karolinska University Hospital, Region Stockholm, Sweden,Umeå Univ, Dept Clin Sci Psychiat, Umeå, Sweden.;Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, SE-17176 Stockholm, Sweden.;Karolinska Univ Hosp, Stockholm Hlth Care Serv, Reg Stockholm, SE-17176 Stockholm, Sweden.
Boström, Adrian Desai E. (författare)
Umeå universitet,Psykiatri,Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Karolinska University Hospital, Region Stockholm, Stockholm, Sweden; Stockholm Health Care Services, Karolinska University Hospital, Region Stockholm, Sweden; Department of Women's and Children's Health/Neuropediatrics, Karolinska Institute, Stockholm, Sweden,Umeå Univ, Dept Clin Sci Psychiat, Umeå, Sweden.;Karolinska Inst, Dept Clin Neurosci, Ctr Psychiat Res, SE-17176 Stockholm, Sweden.;Karolinska Univ Hosp, Stockholm Hlth Care Serv, Reg Stockholm, SE-17176 Stockholm, Sweden.;Karolinska Inst, Dept Womens & Childrens Hlth Neuropediat, Stockholm, Sweden.
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 (creator_code:org_t)
Lippincott Williams & Wilkins, 2023
2023
Engelska.
Ingår i: Journal of ECT. - : Lippincott Williams & Wilkins. - 1095-0680 .- 1533-4112. ; 39:4, s. 227-234
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Major depressive disorder (MDD) is highly prevalent in individuals with anorexia nervosa (AN) and is a predictor of greater clinical severity. However, there is a limited amount of evidence supporting the use of psychotropic medications for its management. A systematic scoping review was conducted to assess the current literature on brain stimulation treatments for AN with comorbid MDD, with a specific focus on MDD treatment response and weight restoration. This review was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, and the PubMed, PsycInfo, and MEDLINE databases were searched until July 2022 using specific key words related to AN and brain stimulation treatments. A total of 373 citations were identified, and 49 treatment studies that met the inclusion criteria were included in the review. The initial evidence suggests that electroconvulsive therapy, repetitive transcranial magnetic stimulation, and deep-brain stimulation may be effective in managing comorbid MDD in AN. Emerging evidence suggests that transcranial direct current stimulation may have a positive effect on body mass index in individuals with severe to extreme AN. However, there is a need for the development of better measurement techniques for assessing the severity of depression in the context of AN. Controlled trials that are adequately designed to account for these limitations are highly warranted for deep-brain stimulation, electroconvulsive therapy, and repetitive transcranial magnetic stimulation and hold promise for providing clinically meaningful results.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)

Nyckelord

severe anorexia nervosa
inpatients
ECT
DBS
MDD
treatment guidelines

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