Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy: Advances in Diagnosis and Treatment

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Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy : Advances in Diagnosis and Treatment

Novak, Iona (författare): Cerebral Palsy Alliance, The University of Sydney, Sydney, Australia

Morgan, Cathy (författare): Cerebral Palsy Alliance, The University of Sydney, Sydney, Australia

Adde, Lars (författare): Norwegian University of Science and Technology, St Olavs University Hospital, Trondheim, Norway

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Blackman, James (författare): Cerebral Palsy Alliance Research Foundation, New York, USA

Boyd, Roslyn N. (författare): The University of Queensland, Brisbane, Australia

Brunstrom-Hernandez, Janice (författare): Children's Medical Center Dallas, Plano, Texas

Cioni, Giovanni (författare): Stella Maris Scientific Institute, University of Pisa, Pisa, Italy

Damiano, Diane (författare): National Institutes of Health, Bethesda, USA

Darrah, Johanna (författare): Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, Canada

Eliasson, Ann-Christin, 1950- (författare): Karolinska Institutet

de Vries, Linda S. (författare): University Medical Centre Utrecht, Utrecht, the Netherlands

Einspieler, Christa (författare): Medical University of Graz, Graz, Austria

Fahey, Michael (författare): Monash University, Melbourne, Australia

Fehlings, Darcy (författare): Holland Bloorview Kids Rehabilitation Hospital, University of Toronto, Toronto, Canada

Ferriero, Donna M. (författare): University of California, San Francisco, USA

Fetters, Linda (författare): University of Southern California, Los Angeles, USA

Fiori, Simona (författare): Stella Maris Scientific Institute, University of Pisa, Pisa, Italy

Forssberg, Hans (författare): Karolinska Institutet

Gordon, Andrew M. (författare): Teachers College, Columbia University, New York, USA

Greaves, Susan (författare): The Royal Children's Hospital, Melbourne, Australia

Guzzetta, Andrea (författare): Stella Maris Scientific Institute, University of Pisa, Pisa, Italy

Hadders-Algra, Mijna (författare): University Medical Center Groningen, University of Groningen, Groningen, the Netherlands

Harbourne, Regina (författare): Duquesne University, Pittsburgh, USA

Kakooza-Mwesige, Angelina (författare): Makerere University, Kampala, Uganda

Karlsson, Petra (författare): Cerebral Palsy Alliance, The University of Sydney, Sydney, Australia

Krumlinde-Sundholm, Lena (författare): Karolinska Institutet

Latal, Beatrice (författare): University Children's Hospital Zurich, Zurich, Switzerland

Loughran-Fowlds, Alison (författare): Children's Hospital Westmead, The University of Sydney, Sydney, Australia

Maitre, Nathalie (författare): Nationwide Children's Hospital, The Ohio State University, Columbus, USA

McIntyre, Sarah (författare): Cerebral Palsy Alliance, The University of Sydney, Sydney, Australia

Noritz, Garey (författare): Nationwide Children's Hospital, The Ohio State University, Columbus, USA

Pennington, Lindsay (författare): Newcastle University, Newcastle Upon Tyne, England

Romeo, Domenico M. (författare): Pediatric Neurology Unit, Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del Sacro Cuore, Rome, Italy

Shepherd, Roberta (författare): The University of Sydney, Sydney, Australia

Spittle, Alicia J. (författare): Murdoch Childrens Research Institute, University of Melbourne, Melbourne, Australia

Thornton, Marelle (författare): Cerebral Palsy Alliance, The University of Sydney, Sydney, Australia

Valentine, Jane (författare): Princess Margaret Hospital, University of Western Australia, Perth

Walker, Karen (författare): Cerebral Palsy Alliance, The University of Sydney, Sydney, Australia; Children's Hospital Westmead, The University of Sydney, Sydney, Australia

White, Robert (författare): Cerebral Palsy Alliance, The University of Sydney, Sydney, Australia

Badawi, Nadia (författare): Cerebral Palsy Alliance, The University of Sydney, Sydney, Australia; Children's Hospital Westmead, The University of Sydney, Sydney, Australia

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(creator_code:org_t)

American Medical Association, 2017
2017
Engelska.
Ingår i: JAMA pediatrics. - : American Medical Association. - 2168-6203 .- 2168-6211. ; 171:9, s. 897-907

Relaterad länk:: https://pure.rug.nl/...; visa fler...; https://urn.kb.se/re...; https://doi.org/10.1...; http://kipublication...; visa färre...

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Importance: Cerebral palsy describes the most common physical disability in childhood and occurs in 1 in 500 live births. Historically, the diagnosis has been made between age 12 and 24 months but now can be made before 6 months' corrected age.Objectives: To systematically review best available evidence for early, accurate diagnosis of cerebral palsy and to summarize best available evidence about cerebral palsy-specific early intervention that should follow early diagnosis to optimize neuroplasticity and function.Evidence Review: This study systematically searched the literature about early diagnosis of cerebral palsy in MEDLINE (1956-2016), EMBASE (1980-2016), CINAHL (1983-2016), and the Cochrane Library (1988-2016) and by hand searching. Search terms included cerebral palsy, diagnosis, detection, prediction, identification, predictive validity, accuracy, sensitivity, and specificity. The study included systematic reviews with or without meta-analyses, criteria of diagnostic accuracy, and evidence-based clinical guidelines. Findings are reported according to the PRISMA statement, and recommendations are reported according to the Appraisal of Guidelines, Research and Evaluation (AGREE) II instrument.Findings: Six systematic reviews and 2 evidence-based clinical guidelines met inclusion criteria. All included articles had high methodological Quality Assessment of Diagnostic Accuracy Studies (QUADAS) ratings. In infants, clinical signs and symptoms of cerebral palsy emerge and evolve before age 2 years; therefore, a combination of standardized tools should be used to predict risk in conjunction with clinical history. Before 5 months' corrected age, the most predictive tools for detecting risk are term-age magnetic resonance imaging (86%-89% sensitivity), the Prechtl Qualitative Assessment of General Movements (98% sensitivity), and the Hammersmith Infant Neurological Examination (90% sensitivity). After 5 months' corrected age, the most predictive tools for detecting risk are magnetic resonance imaging (86%-89% sensitivity) (where safe and feasible), the Hammersmith Infant Neurological Examination (90% sensitivity), and the Developmental Assessment of Young Children (83% C index). Topography and severity of cerebral palsy are more difficult to ascertain in infancy, and magnetic resonance imaging and the Hammersmith Infant Neurological Examination may be helpful in assisting clinical decisions. In high-income countries, 2 in 3 individuals with cerebral palsy will walk, 3 in 4 will talk, and 1 in 2 will have normal intelligence.Conclusions and Relevance: Early diagnosis begins with a medical history and involves using neuroimaging, standardized neurological, and standardized motor assessments that indicate congruent abnormal findings indicative of cerebral palsy. Clinicians should understand the importance of prompt referral to diagnostic-specific early intervention to optimize infant motor and cognitive plasticity, prevent secondary complications, and enhance caregiver well-being.

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Pediatrik

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Neurologi

Artiklar i publikationen: JAMA pediatrics

Av lärosätet: Örebro universitet; Karolinska Institutet

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Early, Accurate Diagnosis and Early Intervention in Cerebral Palsy : Advances in Diagnosis and Treatment

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