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Optimising treatmen...
Optimising treatments for sexually transmitted infections : surveillance, pharmacokinetics and pharmacodynamics, therapeutic strategies, and molecular resistance prediction
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- Seña, Arlene C. (författare)
- Department of Medicine, University of North Carolina, Chapel Hill, NC, USA
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- Bachmann, Laura (författare)
- Department of Medicine, Wake Forest University, Winston Salem, NC, USA; Division of Sexually Transmitted Diseases Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
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- Johnston, Christine (författare)
- Department of Medicine, University of Washington, Seattle, WA, USA
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- Wi, Teodora (författare)
- Global HIV, Hepatitis and Sexually Transmitted Infections Programme, WHO, Geneva, Switzerland
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- Workowski, Kimberly (författare)
- Division of Sexually Transmitted Diseases Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA; Department of Medicine, Emory University, Atlanta, GA, USA
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- Hook, Edward W., 3rd (författare)
- Department of Medicine, University of Alabama, Birmingham, AL, USA
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- Hocking, Jane S. (författare)
- Sexual Health Unit, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia
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- Drusano, George (författare)
- Institute for Therapeutic Innovation, University of Florida, Orlando, FL, USA
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- Unemo, Magnus, 1970- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,WHO Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections and the Swedish Reference Laboratory for STIs, Department of Laboratory Medicine
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(creator_code:org_t)
- Elsevier, 2020
- 2020
- Engelska.
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Ingår i: The Lancet - Infectious diseases. - : Elsevier. - 1473-3099 .- 1474-4457. ; 20:8, s. e181-e191
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Progressive antimicrobial resistance in Neisseria gonorrhoeae, Mycoplasma genitalium, and Trichomonas vaginalis has created a pressing need for treatment optimisations for sexually transmitted infections (STIs). In this Review, we aim to highlight urgent needs in global STI management, including: (1) improved surveillance to monitor antimicrobial resistance and clinical outcomes; (2) systematic pharmacokinetic and pharmacodynamic evaluations to ensure resistance suppression and bacterial eradication at all sites of infection; (3) development of novel, affordable antimicrobials; and (4) advancements in new molecular and point-of-care tests to detect antimicrobial resistance determinants. Antimicrobial resistance among STIs is a global public health crisis. Continuous efforts to develop novel antimicrobials will be essential, in addition to other public health interventions to reduce the global STI burden. Apart from prevention through safer sexual practices, the development of STI vaccines to prevent transmission is a crucial research priority.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
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Seña, Arlene C.
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Bachmann, Laura
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Johnston, Christ ...
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Wi, Teodora
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Workowski, Kimbe ...
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Hook, Edward W., ...
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visa fler...
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Hocking, Jane S.
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Drusano, George
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Unemo, Magnus, 1 ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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The Lancet - Inf ...
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Örebro universitet