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Pre-treatment aller...
Pre-treatment allergen-specific IgE analysis and outcomes of allergen immunotherapy
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- Berge, Martin (författare)
- Department of Otolaryngology, Örebro University Hospital, Örebro, Sweden
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- Bertilsson, Lena (författare)
- Department of Laboratory Medicine, Örebro University Hospital, Örebro, Sweden
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- Hultgren, Olof, 1970- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Laboratory Medicine, Örebro University Hospital, Örebro, Sweden; Department Clinical Immunology and Transfusion Medicine, Faculty of Medicine and Health Örebro University, Örebro, Sweden
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- Hugosson, Svante, 1956- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Otolaryngology, Örebro University Hospital, Örebro, Sweden
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- Saber, Amanj, 1972- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Otolaryngology, Örebro University Hospital, Örebro, Sweden
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(creator_code:org_t)
- Edizioni Edra, 2022
- 2022
- Engelska.
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Ingår i: European annals of allergy and clinical Immunology. - : Edizioni Edra. - 1764-1489. ; 54:5, s. 218-228
- Relaterad länk:
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https://doi.org/10.2...
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https://urn.kb.se/re...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- Background: Patients show varied results to allergen immunotherapy (AIT. The reason for this variability is unclear.Objective: To describe the relationship between AIT efficacy and demographic characteristics, as well as pre-treatment plasma levels of specific IgE-antibodies to grass and birch pollen.Methods: A retrospective study was performed based on medical records of 128 patients who received AIT. The patients completed a questionnaire and pre-AIT plasma levels of allergen-specific IgE to grass and birch pollen were measured using EUROLINE DPA-Dx pollen 1 method. Results. Seventy percent of patients classified their allergic symptoms as less severe after AIT. Twenty-seven percent had received AIT targeting only grass pollen, 19% targeting only birch pollen, and 55% targeting both grass and birch. A total of 35 different IgE profiles were found across our study population. On comparison of the demographic characteristics and concentration of allergen-specific IgE-antibodies, no statistically significant differences could be found.Conclusions: The majority of patients rated their allergic symptoms as less severe after AIT. No clear relationship could be demonstrated between pre-treatment allergen-specific IgE concentration, or demographic characteristics, and effect of AIT. There may be other factors underlying the different responses to AIT.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Nyckelord
- Pollen allergy
- IgE
- allergen immunotherapy
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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