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Disparities in Scre...
Disparities in Screening and Treatment of Cardiovascular Diseases in Patients With Mental Disorders Across the World : Systematic Review and Meta-Analysis of 47 Observational Studies
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- Solmi, Marco (författare)
- University of Padua, Italy, Padua, Italy; King's College London, London, UK
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- Fiedorowicz, Jess (författare)
- University of Ottawa, Ottawa, Canada
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- Poddighe, Laura (författare)
- University of Padua, Italy, Padua, Italy
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- Delogu, Marco (författare)
- University of Padua, Italy, Padua, Italy
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- Miola, Alessandro (författare)
- University of Padua, Italy, Padua, Italy
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- Høye, Anne (författare)
- UiT-Arctic University of Norway, Tromsø, Norway; University Hospital of North Norway, Tromsø, Norway; Center for Clinical Documentation and Evaluation (SKDE), Tromsø, Norway,UiT The Arctic University of Norway, Tromsø
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- Heiberg, Ina H. (författare)
- Center for Clinical Documentation and Evaluation (SKDE), Tromsø, Norway
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- Stubbs, Brendon (författare)
- King's College London, London, UK
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- Smith, Lee (författare)
- Anglia Ruskin University, Cambridge, UK,University of Padova
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- Larsson, Henrik, 1975- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Karolinska Institutet, Stockholm, Sweden,University of Padova
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- Attar, Rubina (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Aalborg University
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- Nielsen, René E. (författare)
- Aalborg University Hospital, Aalborg, Denmark; Aalborg University, Aalborg, Denmark
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- Cortese, Samuele (författare)
- University of Southampton, Southampton, UK; NHS Trust, Southampton, UK; Hassenfeld Children's Hospital at NYU Langone, New York, USA; University Child Study Center, New York, USA; University of Nottingham, Nottingham, UK
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- Shin, Jae Il (författare)
- Yonsei University College of Medicine, Seoul, Korea
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- Fusar-Poli, Paolo (författare)
- King's College London, London, UK; National Institute for Health Research, Maudsley Biomedical Research Centre, Kondon, UK; OASIS Service, London, UK; Maudsley NHS Foundation Trust, London, UK; University of Pavia, Pavia, Italy
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- Firth, Joseph (författare)
- University of Manchester, Manchester Academic Health Science Centre, Manchester, UK; NICM Health Research Institute, Western Sydney University, Westmead, Australia
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- Yatham, Lakshmi N. (författare)
- University of British Columbia, Vancouver, Canada
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- Carvalho, Andre F. (författare)
- Deakin University, Geelong, Australia,University of Padova
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- Castle, David J. (författare)
- University of Toronto, Toronta, Canada; Centre for Addiction and Mental Health, Toronto, Canada
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- Seeman, Mary V. (författare)
- University of Toronto, Toronta, Canada; Centre for Addiction and Mental Health, Toronto, Canada
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- Correll, Christoph U. (författare)
- Charité University Medicine Berlin, Berlin, Germany; Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, USA; Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA
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(creator_code:org_t)
- HighWire Press, 2021
- 2021
- Engelska.
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Ingår i: American Journal of Psychiatry. - : HighWire Press. - 0002-953X .- 1535-7228. ; 178:9, s. 793-803
- Relaterad länk:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- OBJECTIVE: This study used meta-analysis to assess disparities in cardiovascular disease (CVD) screening and treatment in people with mental disorders, a group that has elevated CVD incidence and mortality.METHODS: The authors searched PubMed and PsycInfo through July 31, 2020, and conducted a random-effect meta-analysis of observational studies comparing CVD screening and treatment in people with and without mental disorders. The primary outcome was odds ratios for CVD screening and treatment. Sensitivity analyses on screening and treatment separately and on specific procedures, subgroup analyses by country, and by controlling for confounding by indication, as well as meta-regressions, were also run, and publication bias and quality were assessed.RESULTS: Forty-seven studies (N=24,400,452 patients, of whom 1,283,602 had mental disorders) from North America (k=26), Europe (k=16), Asia (k=4), and Australia (k=1) were meta-analyzed. Lower rates of screening or treatment in patients with mental disorders emerged for any CVD (k=47, odds ratio=0.773, 95% CI=0.742, 0.804), coronary artery disease (k=34, odds ratio=0.734, 95% CI=0.690, 0.781), cerebrovascular disease (k=8, odds ratio=0.810, 95% CI=0.779, 0.842), and other mixed CVDs (k=11, odds ratio=0.839, 95% CI=0.761, 0.924). Significant disparities emerged for any screening, any intervention, catheterization or revascularization in coronary artery disease, intravenous thrombolysis for stroke, and treatment with any and with specific medications for CVD across all mental disorders (except for CVD medications in mood disorders). Disparities were largest for schizophrenia, and they differed across countries. Median study quality was high (Newcastle-Ottawa Scale score, 8); higher-quality studies found larger disparities, and publication bias did not affect results.CONCLUSIONS: People with mental disorders, and those with schizophrenia in particular, receive less screening and lower-quality treatment for CVD. It is of paramount importance to address underprescribing of CVD medications and underutilization of diagnostic and therapeutic procedures across all mental disorders.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Bipolar and Related Disorders
- Cardiovascular Disease
- Mental Health Care/Service Delivery Systems
- Physical Health
- Schizophrenia Spectrum and Other Psychotic Disorders
- Screening
- Bipolar and Related Disorders
- Cardiovascular Disease
- Mental Health Care/Service Delivery Systems
- Physical Health
- Schizophrenia Spectrum and Other Psychotic Disorders
- Screening
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Solmi, Marco
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Fiedorowicz, Jes ...
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Poddighe, Laura
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Delogu, Marco
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Miola, Alessandr ...
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Høye, Anne
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visa fler...
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Heiberg, Ina H.
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Stubbs, Brendon
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Smith, Lee
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Larsson, Henrik, ...
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Attar, Rubina
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Nielsen, René E.
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Cortese, Samuele
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Shin, Jae Il
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Fusar-Poli, Paol ...
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Firth, Joseph
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Yatham, Lakshmi ...
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Carvalho, Andre ...
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Castle, David J.
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Seeman, Mary V.
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Correll, Christo ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Psykiatri
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
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American Journal ...
- Av lärosätet
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Örebro universitet
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Lunds universitet
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Karolinska Institutet