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Lumbar spine abnorm...
Lumbar spine abnormalities in patients with obstructive sleep apnoea
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- Tarnoki, Adam Domonkos (författare)
- Medical Imaging Centre, Semmelweis University, Budapest, Hungary
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- Tarnoki, David Laszlo (författare)
- Medical Imaging Centre, Semmelweis University, Budapest, Hungary
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- Oláh, Csaba (författare)
- Department of Neurosurgery, Borsod-Abaúj-Zemplén County and University Teaching Hospital, Miskolc, Hungary
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- Szily, Marcell (författare)
- Medical Imaging Centre, Semmelweis University, Budapest, Hungary
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- Kovacs, Daniel T. (författare)
- Medical Imaging Centre, Semmelweis University, Budapest, Hungary
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- Dienes, András (författare)
- Medical Imaging Centre, Semmelweis University, Budapest, Hungary
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- Piroska, Marton (författare)
- Medical Imaging Centre, Semmelweis University, Budapest, Hungary
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- Forgo, Bianka, 1992- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Radiology
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- Pinheiro, Marina (författare)
- Faculty of Health Sciences, Discipline of Physiotherapy, The University of Sydney, Musculoskeletal Health, Sydney, Australia
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- Ferreira, Paulo (författare)
- Faculty of Health Sciences, Discipline of Physiotherapy, The University of Sydney, Musculoskeletal Health, Sydney, Australia
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- Kostyál, László (författare)
- Department of Neurosurgery, Borsod-Abaúj-Zemplén County and University Teaching Hospital, Miskolc, Hungary
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- Meszaros, Martina (författare)
- Department of Pulmonology, Semmelweis University, Budapest, Hungary; Department of Pulmonology, University Hospital Zurich, Zurich, Switzerland
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- Pako, Judit (författare)
- National Koranyi Institute for Pulmonology, Budakeszi, Hungary
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- Kunos, Laszlo (författare)
- Department of Pulmonology, Semmelweis University, Budapest, Hungary
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- Bikov, Andras (författare)
- Department of Pulmonology, Semmelweis University, Budapest, Hungary; Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK
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(creator_code:org_t)
- 2021-08-10
- 2021
- Engelska.
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Ingår i: Scientific Reports. - : Nature Publishing Group. - 2045-2322. ; 11:1
- Relaterad länk:
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https://doi.org/10.1...
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https://www.nature.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Previous studies suggested cervical spondylosis as a risk factor for development of obstructive sleep apnoea (OSA). We aimed to assess lumbar disc degeneration in patients with OSA and correlate the findings with symptoms and disease severity. Twenty-seven patients with OSA and 29 non-OSA controls underwent sleep studies and lumbar magnetic resonance imaging (MRI), and completed the Epworth Sleepiness Scale and the 24-item Roland-Morris Disability Questionnaire (RMDQ) questionnaires. Plasma klotho was determined with enzyme-linked immunosorbent assay. Patients with OSA had higher number of disc bulges (4.6 ± 3.7 vs. 1.7 ± 2.5, p < 0.01) and anterior spondylophytes (2.7 ± 4.2 vs. 0.8 ± 2.1, p < 0.01), increased disc degeneration (total Pfirrmann score 16.7 ± 4.7 vs. 13.2 ± 4.1, p < 0.01) and vertebral fatty degeneration (7.8 ± 4.7 vs. 3.8 ± 3.7, p < 0.01). There was no difference in the RMDQ score (0/0-3.5/ vs. 0/0-1/, p > 0.05). Markers of OSA severity, including the oxygen desaturation index and percentage of total sleep time spent with saturation < 90% as well as plasma levels of klotho were correlated with the number of disc bulges and anterior spondylophytes (all p < 0.05). OSA is associated with lumbar spondylosis. Our study highlights the importance of lumbar imaging in patients with OSA reporting lower back pain.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
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Tarnoki, Adam Do ...
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Tarnoki, David L ...
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Oláh, Csaba
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Szily, Marcell
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Kovacs, Daniel T ...
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Dienes, András
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Piroska, Marton
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Forgo, Bianka, 1 ...
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Pinheiro, Marina
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Ferreira, Paulo
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Kostyál, László
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Meszaros, Martin ...
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Pako, Judit
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Kunos, Laszlo
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Bikov, Andras
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Örebro universitet