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Sökning: WFRF:(de la Cruz Lorena Fernández) > Insomnia in Tourett...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004814naa a2200493 4500
001oai:DiVA.org:oru-95179
003SwePub
008211027s2022 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:147930859
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-951792 URI
0247 a https://doi.org/10.1002/mds.288422 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1479308592 URI
040 a (SwePub)orud (SwePub)ki
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Isomura, Kayokou Karolinska Institutet4 aut
2451 0a Insomnia in Tourette Syndrome and Chronic Tic Disorder
264 c 2021-10-24
264 1b John Wiley & Sons,c 2022
338 a print2 rdacarrier
520 a BACKGROUND: Insomnia is common in Tourette syndrome (TS) and chronic tic disorder (CTD), but precise prevalence estimates are lacking.OBJECTIVE: In this Swedish register-based cohort study, we estimated the prevalence of insomnia in TS/CTD and quantified the magnitude of this association, accounting for familial confounders and relevant somatic and psychiatric comorbidities.METHODS: Of 10,444,702 individuals living in Sweden during the period from 1997 to 2013, 5877 had a diagnosis of TS/CTD and were compared to unexposed individuals from the general population on the presence of insomnia using logistic regression models.RESULTS: Individuals with TS/CTD had a period prevalence of insomnia of 32.16%, compared to 13.70% of the unexposed population. This translated into a 6.7-fold increased likelihood of insomnia in TS/CTD (odds ratio adjusted [aOR] for sex, birth year, birth country, and somatic disorders = 6.74; 95% confidence interval [CI], 6.37-7.15). A full sibling comparison, designed to adjust for shared familial factors, attenuated the estimates (aOR = 5.41; 95% CI, 4.65-6.30). When individuals with attention-deficit/hyperactivity disorder (ADHD) and pervasive developmental disorders were excluded, the association was also attenuated, whereas exclusion of other psychiatric comorbidities had minimal impact. Having persistent TS/CTD, comorbid ADHD, and taking ADHD medication greatly increased the likelihood of insomnia.CONCLUSIONS: Insomnia is significantly associated with TS/CTD, independently from somatic disorders, familial factors or psychiatric comorbidities, although familial factors, neurodevelopmental comorbidities, and ADHD/ADHD medication may explain part of the association. Insomnia should be routinely assessed and managed in TS/CTD, particularly in chronic patients and in those with comorbid ADHD. Other sleep disorders require further study. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng
653 a Tourette syndrome
653 a attention-deficit/hyperactivity disorder
653 a chronic tic disorder
653 a insomnia
653 a sleep problems
7001 a Sidorchuk, Annau Karolinska Institutet4 aut
7001 a Sevilla-Cermeño, Laurau Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, CIBERSAM, Madrid, Spain4 aut
7001 a Åkerstedt, Torbjörnu Karolinska Institutet4 aut
7001 a Silverberg-Morse, Mariau Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden4 aut
7001 a Larsson, Henrik,d 1975-u Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden4 aut0 (Swepub:oru)hiln
7001 a Mataix-Cols, Davidu Karolinska Institutet4 aut
7001 a Fernández de la Cruz, Lorenau Karolinska Institutet4 aut
7102 a Karolinska Institutetb Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, IiSGM, CIBERSAM, Madrid, Spain4 org
7730 t Movement Disordersd : John Wiley & Sonsg 37:2, s. 392-400q 37:2<392-400x 0885-3185x 1531-8257
8564 u https://doi.org/10.1002/mds.28842y Fulltext
8564 u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.28842
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-95179
8564 8u https://doi.org/10.1002/mds.28842
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:147930859

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