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Search: WFRF:(Kärrman Anna 1975 ) > (2020-2024) > Pioneering an effec...

Pioneering an effect-based early warning system for hazardous chemicals in the environment

Niarchos, Georgios (author)
Dept. of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences, Uppsala, Sweden
Alygizakis, Nikiforos (author)
Dept. of Chemistry, National and Kapodistrian University of Athens, Panepistimioupoli Zografou, Athens, Greece
Carere, Mario (author)
Dept. of Environment and Health, Italian National Institute of Health, Rome, Italy
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Dulio, Valeria (author)
NERIS, Parc Technologique ALATA, Verneuil-en-Halatte, France
Engwall, Magnus, 1965- (author)
Örebro universitet,Institutionen för naturvetenskap och teknik
Hyötyläinen, Tuulia, 1971- (author)
Örebro universitet,Institutionen för naturvetenskap och teknik
Kallenborn, Roland (author)
Faculty of Chemistry, Biotechnology and Food Sciences (KBM), Norwegian University of Life Sciences, Ås, Norway
Karakitsios, Spyros (author)
Dept. of Chemical Engineering, Environmental Engineering Laboratory, Aristotle University of Thessaloniki, University Campus, Thessaloniki, Greece
Karakoltzidis, Achilleas (author)
Dept. of Chemical Engineering, Environmental Engineering Laboratory, Aristotle University of Thessaloniki, University Campus, Thessaloniki, Greece
Kärrman, Anna, 1975- (author)
Örebro universitet,Institutionen för naturvetenskap och teknik
Lamoree, Marja (author)
Amsterdam Institute for Life and Environment (A-LIFE), Section Chemistry for Environment & Health, Vrije Universiteit, Amsterdam, the Netherlands
Larsson, Maria, 1975- (author)
Örebro universitet,Institutionen för naturvetenskap och teknik
Lundqvist, Johan (author)
Dept. of Animal Biosciences, Swedish University of Agricultural Sciences, Uppsala, Sweden
Mancini, Laura (author)
Dept. of Environment and Health, Italian National Institute of Health, Rome, Italy
Mottaghipisheh, Javad (author)
Dept. of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences, Uppsala, Sweden
Rostkowski, Pawel (author)
Dept. of Environmental Chemistry and Health Effects, NILU, Kjeller, Norway
Sarigiannis, Dimosthenis (author)
Dept. of Chemical Engineering, Environmental Engineering Laboratory, Aristotle University of Thessaloniki, University Campus, Thessaloniki, Greece
Vorkamp, Katrin (author)
Dept. of Environmental Science, Aarhus University, Roskilde, Denmark
Ahrens, Lutz (author)
Dept. of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences, Uppsala, Sweden
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Dept of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences, Uppsala, Sweden Dept. of Chemistry, National and Kapodistrian University of Athens, Panepistimioupoli Zografou, Athens, Greece (creator_code:org_t)
Elsevier, 2024
2024
English.
In: TrAC. Trends in analytical chemistry. - : Elsevier. - 0165-9936 .- 1879-3142. ; 180
Related links:
https://doi.org/10.1...
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https://urn.kb.se/re...
https://doi.org/10.1...
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  • Research review (peer-reviewed)
Abstract Subject headings
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  • Existing regulatory frameworks often prove inadequate in identifying contaminants of emerging concern (CECs) and determining their impacts on biological systems at an early stage. The establishment of Early Warning Systems (EWSs) for CECs is becoming increasingly relevant for policy-making, aiming to proactively detect chemical hazards and implement effective mitigation measures. Effect-based methodologies, including bioassays and effect-directed analysis (EDA), offer valuable input to EWSs with a view to pinpointing the relevant toxicity drivers and prioritizing the associated risks. This review evaluates the analytical techniques currently available to assess biological effects, and provides a structured plan for their systematic integration into an EWS for hazardous chemicals in the environment. Key scientific advancements in effect-based approaches and EDA are discussed, underscoring their potential for early detection and management of chemical hazards. Additionally, critical challenges such as data integration and regulatory alignment are addressed, emphasizing the need for continuous improvement of the EWS and the incorporation of analytical advancements to safeguard environmental and public health from emerging chemical threats.

Subject headings

NATURVETENSKAP  -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
NATURAL SCIENCES  -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)

Keyword

Contaminants of emerging concern
Bioassays
Effect-based methods
Effect-directed analysis
Environmental monitoring
Toxicity

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