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Sökning: (WFRF:(Ole Brus)) pers:(Nordenskjöld Axel) > (2020-2024) > Suicidal ideation a...

  • Sienaert, PascalDepartment of Neurosciences, University Psychiatric Center KU Leuven and Research Group Psychiatry, Academic Center for ECT and Neuromodulation (AcCENT), Faculty of Medicine, University of Leuven, Leuven, Belgium,Katholieke Univ Leuven, Belgium; Univ Leuven, Belgium (författare)

Suicidal ideation and ECT, ECT and suicidal ideation : a register study

  • Artikel/kapitelEngelska2022

Förlag, utgivningsår, omfång ...

  • 2022-03-18
  • Wiley-Blackwell Publishing Inc.2022
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:oru-97984
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-97984URI
  • https://doi.org/10.1111/acps.13425DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:149074642URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-183898URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Funding Agencies|Region Orebro lan
  • OBJECTIVE: Although electroconvulsive therapy (ECT) is anti-suicidal, it is not known whether the presence of suicidal ideation (SI) at baseline predicts response and remission after ECT. The aim of the study was to analyze the impact of baseline SI on response and remission following ECT treatment in a large sample of patients with depression and to assess SI before and after ECT.METHODS: This population-based register study used data from the Swedish National Quality Register for ECT and the Swedish Patient Register. Patients aged 18 years or older who had received ECT for a unipolar or bipolar depressive episode between 2011 and 2018 were included in the study. SI was defined as a score of ≥ 4 on the last item of the Montgomery-Åsberg Depression Rating Scale - Self Assessment (MADRS-S). Using a logistic regression model, SI at baseline was used to predict response and remission following ECT, while controlling for depression severity, psychotic symptoms, presence of a comorbid personality disorder, age, sex, electrode position, unipolar or bipolar disorder, and number of previous suicide attempts at baseline.RESULTS: In patients who exhibited SI at baseline, 53.7% (N = 632) of cases showed a response to ECT, whereas 68.4% (N = 690) of patients without SI showed a response. In addition, 27.2% (N = 320) of cases with SI achieved remission, whereas 48.5% (N = 489) of cases without SI achieved remission. The odds of achieving response and remission for patients with SI were 0.75 and 0.58 times, respectively, those for patients without SI. Of the 1178 patients with pre-treatment SI, 75.64% (N = 891) exhibited no SI at the end of treatment. Moreover, in this subgroup, the presence of a personality disorder, higher MADRS-S-score, and younger age were associated with persistent SI.CONCLUSION: The presence of SI was associated with lower ECT response and remission rates. Nevertheless, depressive symptoms and SI were reduced in a large proportion of patients across both patient groups. Clinicians should be aware of the lower likelihood of achieving a successful outcome following ECT in younger patients who present with a non-psychotic depressive episode, SI, and (suspected) personality disorders. More research is warranted regarding if these patients can achieve similar or better results with other treatments.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Brus, Ole,1982-Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology and Biostatistics,Örebro Univ, Sweden(Swepub:oru)oebs (författare)
  • Lambrichts, SimonDepartment of Neurosciences, University Psychiatric Center KU Leuven and Research Group Psychiatry, Academic Center for ECT and Neuromodulation (AcCENT), Faculty of Medicine, University of Leuven, Leuven, Belgium,Katholieke Univ Leuven, Belgium; Univ Leuven, Belgium (författare)
  • Lundberg, JohanKarolinska Institutet,Karolinska Inst, Sweden; Stockholm Cty Council, Sweden (författare)
  • Nordanskog, PiaLinköpings universitet,Centrum för social och affektiv neurovetenskap,Medicinska fakulteten,Region Östergötland, Psykiatriska kliniken i Linköping,Dept Psychiat, Sweden(Swepub:liu)piano33 (författare)
  • Obbels, JasmienDepartment of Neurosciences, University Psychiatric Center KU Leuven and Research Group Psychiatry, Academic Center for ECT and Neuromodulation (AcCENT), Faculty of Medicine, University of Leuven, Leuven, Belgium,Katholieke Univ Leuven, Belgium; Univ Leuven, Belgium (författare)
  • Verspecht, ShauniDepartment of Neurosciences, University Psychiatric Center KU Leuven and Research Group Psychiatry, Academic Center for ECT and Neuromodulation (AcCENT), Faculty of Medicine, University of Leuven, Leuven, Belgium,Katholieke Univ Leuven, Belgium; Univ Leuven, Belgium (författare)
  • Vansteelandt, KristofDepartment of Neurosciences, University Psychiatric Center KU Leuven and Research Group Psychiatry, Academic Center for ECT and Neuromodulation (AcCENT), Faculty of Medicine, University of Leuven, Leuven, Belgium,Katholieke Univ Leuven, Belgium; Univ Leuven, Belgium (författare)
  • Nordenskjöld, Axel,1977-Örebro universitet,Institutionen för medicinska vetenskaper,University Health Care Research Centre,Örebro Univ, Sweden(Swepub:oru)alnd (författare)
  • Department of Neurosciences, University Psychiatric Center KU Leuven and Research Group Psychiatry, Academic Center for ECT and Neuromodulation (AcCENT), Faculty of Medicine, University of Leuven, Leuven, BelgiumKatholieke Univ Leuven, Belgium; Univ Leuven, Belgium (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Acta Psychiatrica Scandinavica: Wiley-Blackwell Publishing Inc.146:1, s. 74-840001-690X1600-0447

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