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5-Year Outcomes of ...
5-Year Outcomes of PCI Guided by Measurement of Instantaneous Wave-Free Ratio Versus Fractional Flow Reserve
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- Götberg, Matthias (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Cardiol, Clin Sci, S-22141 Lund, Sweden.
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- Berntorp, Karolina (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Cardiol, Clin Sci, S-22141 Lund, Sweden.
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- Rylance, Rebecca (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Cardiol, Clin Sci, S-22141 Lund, Sweden.
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- Christiansen, Evald H. (författare)
- Department of Cardiology, Aarhus University Hospital, Skejby, Denmark,Aarhus Univ Hosp, Dept Cardiol, Skejby, Denmark.
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- Yndigegn, Troels (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Cardiol, Clin Sci, S-22141 Lund, Sweden.
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- Gudmundsdottir, Ingibjörg J. (författare)
- Karolinska Institutet,Karolinska Institute,Capio St. Görans Sjukhus,Univ Iceland, Univ Hosp, Dept Cardiol, Reykjavik, Iceland.,Karolinska Inst, Dept Cardiol, St Goran Hosp, Stockholm, Sweden.
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- Koul, Sasha (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Cardiol, Clin Sci, S-22141 Lund, Sweden.
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- Sandhall, Lennart (författare)
- Department of Cardiology and Radiology, Helsingborg County Hospital, Helsingborg, Sweden,Helsingborg Cty Hosp, Dept Cardiol & Radiol, Helsingborg, Sweden.
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- Danielewicz, Mikael (författare)
- Department of Cardiology, Karlstad Central Hospital, Karlstad, Sweden,Karlstad Cent Hosp, Dept Cardiol, Karlstad, Sweden.
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- Jakobsen, Lars (författare)
- Department of Cardiology, Aarhus University Hospital, Skejby, Denmark,Aarhus Univ Hosp, Dept Cardiol, Skejby, Denmark.
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- Olsson, Sven Erik (författare)
- Department of Cardiology and Radiology, Helsingborg County Hospital, Helsingborg, Sweden,Helsingborg Cty Hosp, Dept Cardiol & Radiol, Helsingborg, Sweden.
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- Olsson, Hans (författare)
- Department of Cardiology, Karlstad Central Hospital, Karlstad, Sweden,Karlstad Cent Hosp, Dept Cardiol, Karlstad, Sweden.
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- Omerovic, Elmir (författare)
- Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Cardiol, Gothenburg, Sweden.
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- Calais, Fredrik, 1971- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Örebro University Hospital, Faculty of Health, Department of Cardiology, Örebro, Sweden; Department of Clinical Medicine, Aarhus University Health, Aarhus, Denmark; Department of Clinical Pharmacology, Aarhus University Hospital, Aarhus, Denmark; Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark,Örebro Univ Hosp, Fac Hlth, Dept Cardiol, Örebro, Sweden.;Aarhus Univ Hlth, Dept Clin Med, Aarhus, Denmark.;Aarhus Univ Hosp, Dept Clin Pharmacol, Aarhus, Denmark.;Aarhus Univ Hosp, Steno Diabet Ctr Aarhus, Aarhus, Denmark.
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- Lindroos, Pontus (författare)
- Department of Cardiology, St Göran Hospital, Stockholm, Sweden,Capio St. Görans Sjukhus,St Goran Hosp, Dept Cardiol, Stockholm, Sweden.
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- Maeng, Michael (författare)
- Department of Cardiology, Aarhus University Hospital, Skejby, Denmark,Aarhus Univ Hosp, Dept Cardiol, Skejby, Denmark.
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- Venetsanos, Dimitrios (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
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- James, Stefan, 1964- (författare)
- Uppsala universitet,Uppsala University,Kardiologi,Uppsala Univ, Sweden
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- Kåregren, Amra (författare)
- Department of Cardiology, Västmanland Hospital, Västerås, Sweden,Vastmanland Hosp, Dept Cardiol, Västerås, Sweden.
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- Carlsson, Jörg (författare)
- Department of Cardiology, Kalmar Hospital, Kalmar, Sweden,Kalmar County Hospital,Kalmar Hosp, Dept Cardiol, Kalmar, Sweden.
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- Jensen, Jens (författare)
- Department of Cardiology, St Göran Hospital, Karolinska Institute, Stockholm, Sweden
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- Karlsson, Ann-Charlotte (författare)
- Department of Cardiology, Halmstad Hospital, Halmstad, Sweden,Halmstad County Hospital,Halmstad Cty Hosp, Dept Cardiol, Halmstad, Sweden.
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- Erlinge, David (författare)
- Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Cardiol, Clin Sci, S-22141 Lund, Sweden.
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- Fröbert, Ole, 1964- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Örebro University Hospital, Faculty of Health, Department of Cardiology, Örebro, Sweden; Department of Clinical Medicine, Aarhus University Health, Aarhus, Denmark; Department of Clinical Pharmacology, Aarhus University Hospital, Aarhus, Denmark; Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark,Örebro Univ Hosp, Fac Hlth, Dept Cardiol, Örebro, Sweden.;Aarhus Univ Hlth, Dept Clin Med, Aarhus, Denmark.;Aarhus Univ Hosp, Dept Clin Pharmacol, Aarhus, Denmark.;Aarhus Univ Hosp, Steno Diabet Ctr Aarhus, Aarhus, Denmark.
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(creator_code:org_t)
- Elsevier, 2022
- 2022
- Engelska.
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Ingår i: Journal of the American College of Cardiology. - : Elsevier. - 0735-1097 .- 1558-3597. ; 79:10, s. 965-974
- Relaterad länk:
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Instantaneous wave-free ratio (iFR) is a coronary physiology index used to assess the severity of coronary artery stenosis to guide revascularization. iFR has previously demonstrated noninferior short-term outcome compared to fractional flow reserve (FFR), but data on longer-term outcome have been lacking.OBJECTIVES: The purpose of this study was to investigate the prespecified 5-year follow-up of the primary composite outcome of all-cause mortality, myocardial infarction, and unplanned revascularization of the iFR-SWEDEHEART trial comparing iFR vs FFR in patients with chronic and acute coronary syndromes.METHODS: iFR-SWEDEHEART was a multicenter, controlled, open-label, registry-based randomized clinical trial using the Swedish Coronary Angiography and Angioplasty Registry for enrollment. A total of 2,037 patients were randomized to undergo revascularization guided by iFR or FFR.RESULTS: No patients were lost to follow-up. At 5 years, the rate of the primary composite endpoint was 21.5% in the iFR group and 19.9% in the FFR group (HR: 1.09; 95% CI: 0.90-1.33). The rates of all-cause death (9.4% vs 7.9%; HR: 1.20; 95% CI: 0.89-1.62), nonfatal myocardial infarction (5.7% vs 5.8%; HR: 1.00; 95% CI: 0.70-1.44), and unplanned revascularization (11.6% vs 11.3%; HR: 1.02; 95% CI: 0.79-1.32) were also not different between the 2 groups. The outcomes were consistent across prespecified subgroups.CONCLUSIONS: In patients with chronic or acute coronary syndromes, an iFR-guided revascularization strategy was associated with no difference in the 5-year composite outcome of death, myocardial infarction, and unplanned revascularization compared with an FFR-guided revascularization strategy. (Evaluation of iFR vs FFR in Stable Angina or Acute Coronary Syndrome [iFR SWEDEHEART]; NCT02166736)
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- coronary physiology
- fractional flow reserve
- instantaneous wave-free ratio
- percutaneous coronary intervention
- coronary physiology
- fractional flow reserve
- instantaneous wave-free ratio
- percutaneous coronary intervention
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Götberg, Matthia ...
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Berntorp, Karoli ...
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Rylance, Rebecca
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Christiansen, Ev ...
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Yndigegn, Troels
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Gudmundsdottir, ...
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visa fler...
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Koul, Sasha
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Sandhall, Lennar ...
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Danielewicz, Mik ...
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Jakobsen, Lars
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Olsson, Sven Eri ...
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Olsson, Hans
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Omerovic, Elmir
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Calais, Fredrik, ...
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Lindroos, Pontus
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Maeng, Michael
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Venetsanos, Dimi ...
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James, Stefan, 1 ...
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Kåregren, Amra
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Carlsson, Jörg
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Jensen, Jens
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Karlsson, Ann-Ch ...
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Erlinge, David
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Fröbert, Ole, 19 ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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Journal of the A ...
- Av lärosätet
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Örebro universitet
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Lunds universitet
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Uppsala universitet
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Linköpings universitet
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Karolinska Institutet