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Impact on follow-up...
Impact on follow-up strategies in patients with primary sclerosing cholangitis
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- Bergquist, Annika (författare)
- Karolinska Institutet,Karolinska University Hospital
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- Weismüller, Tobias J. (författare)
- Department of Internal Medicine I, University Hospital Bonn, University of Bonn, Bonn, Germany,Univ Bonn, Univ Hosp Bonn, Dept Internal Med 1, Bonn, Germany.
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- Levy, Cynthia (författare)
- Division of Digestive Health and Liver Diseases, University of Miami, Miami, FL, USA; Schiff Center for Liver Diseases, University of Miami, Miami, FL, USA,Division of Digestive Health and Liver Diseases, University of Miami, FL, United States; Schiff Center for Liver Diseases, University of Miami, FL, United States,Univ Miami, Div Digest Hlth & Liver Dis, Miami, FL USA.;Univ Miami, Schiff Ctr Liver Dis, Miami, FL USA.
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visa fler...
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- Rupp, Christian (författare)
- Department of Gastroenterology, Infectious Diseases, Intoxication, Heidelberg University Hospital, Heidelberg, Germany,Heidelberg Univ Hosp, Dept Gastroenterol Infect Dis Intoxicat, Heidelberg, Germany.
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- Joshi, Deepak (författare)
- Institute of Liver Studies, King's College Hospital, London, United Kingdom,Kings Coll Hosp London, Inst Liver Studies, London, England.
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- Nayagam, Jeremy Shanika (författare)
- Institute of Liver Studies, King's College Hospital, London, United Kingdom,Kings Coll Hosp London, England; Pomeranian Med Univ, Poland,Kings Coll Hosp London, Inst Liver Studies, London, England.
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- Montano-Loza, Aldo J. (författare)
- Division of Gastroenterology and Liver Unit, Department of Medicine, University of Alberta, AB, Edmonton, Canada,Univ Alberta, Dept Med, Div Gastroenterol, Liver Unit, Edmonton, AB, Canada.
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- Lytvyak, Ellina (författare)
- Division of Gastroenterology and Liver Unit, Department of Medicine, University of Alberta, AB, Edmonton, Canada,Univ Alberta, Dept Med, Div Gastroenterol, Liver Unit, Edmonton, AB, Canada.
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- Wunsch, Ewa (författare)
- Translational Medicine Group, Pomeranian Medical University in Szczecin, Szczecin, Poland,Med Univ Warsaw, Poland,Pomeranian Med Univ, Translat Med Grp, Szczecin, Poland.
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- Milkiewicz, Piotr (författare)
- Translational Medicine Group, Pomeranian Medical University in Szczecin, Szczecin, Poland; Liver and Internal Medicine Unit, Medical University of Warsaw, Warsaw, Poland,Pomeranian Med Univ, Translat Med Grp, Szczecin, Poland.;Med Univ Warsaw, Liver & Internal Med Unit, Warsaw, Poland.
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- Zenouzi, Roman (författare)
- Department of Medicine and Martin Zeitz Center for Rare Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany,Univ Med Ctr Hamburg Eppendorf, Martin Zeitz Ctr Rare Dis, Dept Med, Hamburg, Germany.
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- Schramm, Christoph (författare)
- Department of Medicine and Martin Zeitz Center for Rare Diseases, University Medical Center Hamburg-Eppendorf, Hamburg, Germany,Univ Med Ctr Hamburg Eppendorf, Martin Zeitz Ctr Rare Dis, Dept Med, Hamburg, Germany.
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- Cazzagon, Nora (författare)
- Department of Surgery, Oncology and Gastroenterology, University of Padova, , Padova, Italy and European Reference Network on Hepatological Disease, European Reference Network for Hepatological Diseases, Azienda Ospedaliera-Università di Padova, Padova, Italy,Univ Padua, Dept Surg Oncol & Gastroenterol, Padua, Italy.;Univ Padua, Azienda Ospedaliera, European Reference Network Hepatol Dis, Padua, Italy.,University Hospital of Padua
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- Floreani, Annarosa (författare)
- Studiosa Senior University of Padova, Italy and Scientific Consultant IRCCS Negrar, Verona, Italy,Univ Padua, Sci Consultant IRCCS Negrar, Verona, Italy.
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- Friis Liby, Ingalill (författare)
- Department of Gastroenterology and Hepatology, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Gastroenterol & Hepatol, Gothenburg, Sweden.
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- Wiestler, Miriam (författare)
- Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany; European Reference Network for Hepatological Diseases, Hannover, Germany,Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, Hannover, Germany.;European Reference Network Hepatol Dis, Hannover, Germany.
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- Wedemeyer, Heiner (författare)
- Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany; European Reference Network for Hepatological Diseases, Hannover, Germany,Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, Hannover, Germany.;European Reference Network Hepatol Dis, Hannover, Germany.
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- Zhou, Taotao (författare)
- Department of Internal Medicine I, University Hospital Bonn, University of Bonn, Bonn, Germany,Univ Bonn, Univ Hosp Bonn, Dept Internal Med 1, Bonn, Germany.
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- Strassburg, Christian P. (författare)
- Department of Internal Medicine I, University Hospital Bonn, University of Bonn, Bonn, Germany,Univ Bonn, Univ Hosp Bonn, Dept Internal Med 1, Bonn, Germany.
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- Rigopoulou, Eirini (författare)
- Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece,Gen Univ Hosp Larissa, Natl Expertise Ctr Greece Autoimmune Liver Dis, Dept Med & Res Lab Internal Med, Larisa, Greece.
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- Dalekos, George (författare)
- Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece,Gen Univ Hosp Larissa, Natl Expertise Ctr Greece Autoimmune Liver Dis, Dept Med & Res Lab Internal Med, Larisa, Greece.
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- Narasimman, Manasa (författare)
- Schiff Center for Liver Diseases, University of Miami, Miami, FL, USA,Schiff Center for Liver Diseases, University of Miami, FL, United States,Univ Miami, Schiff Ctr Liver Dis, Miami, FL USA.
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- Verhelst, Xavier (författare)
- Department of Gastroenterology and Hepatology, Ghent University Hospital, Ghent, Belgium; Ghent Liver Research Center, Ghent University, Ghent, Belgium; European Reference Network for Hepatological Diseases, Ghent, Belgium,Ghent Univ Hosp, Dept Gastroenterol & Hepatol, Ghent, Belgium.;Univ Ghent, Ghent Liver Res Ctr, Ghent, Belgium.;European Reference Network Hepatol Dis, Ghent, Belgium.
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- Degroote, Helena (författare)
- Department of Gastroenterology and Hepatology, Ghent University Hospital, Ghent, Belgium; Ghent Liver Research Center, Ghent University, Ghent, Belgium; European Reference Network for Hepatological Diseases, Ghent, Belgium,Ghent Univ Hosp, Dept Gastroenterol & Hepatol, Ghent, Belgium.;Univ Ghent, Ghent Liver Res Ctr, Ghent, Belgium.;European Reference Network Hepatol Dis, Ghent, Belgium.
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- Vesterhus, Mette (författare)
- Norwegian PSC Research Centre, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway; Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Medicine, Haraldsplass Deaconess Hospital, Bergen, Norway,Oslo Univ Hosp, Norwegian PSC Res Ctr, Div Surg Inflammatory Dis & Transplantat, Rikshosp,Dept Transplantat Med, Oslo, Norway.;Univ Bergen, Dept Clin Sci, Bergen, Norway.;Haraldsplass Deaconess Hosp, Dept Med, Bergen, Norway.,Norwegian Radium Hospital
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- Kremer, Andreas E (författare)
- Department of Medicine 1, Friedrich-Alexander-University Erlangen-Nürnberg and University Hospital Erlangen, Erlangen, Germany; Department of Gastroenterology and Hepatology, University Hospital Zürich, Zürich, Switzerland,Friedrich Alexander Univ Erlangen Nurnberg, Dept Med 1, Erlangen, Germany.;Univ Hosp Erlangen, Erlangen, Germany.;Univ Hosp Zurich, Dept Gastroenterol & Hepatol, Zurich, Switzerland.
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- Bündgens, Bennet (författare)
- Department of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany,Univ Duisburg, Univ Hosp Essen, Dept Gastroenterol & Hepatol, Essen, Germany.
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- Rorsman, Fredrik, Docent, 1960- (författare)
- Uppsala universitet,Gastroenterologi/hepatologi,Uppsala University Hospital
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- Nilsson, Emma (författare)
- Lund University,Lunds universitet,Gastro,Forskargrupper vid Lunds universitet,Lund University Research Groups,Skåne University Hospital
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- Jørgensen, Kristin Kaasen (författare)
- Department of Gastroenterology, Akershus University Hospital, Lørenskog, Norway,Akershus Univ Hosp, Dept Gastroenterol, Lorenskog, Norway.
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- von Seth, Erik (författare)
- Karolinska Institutet,Karolinska University Hospital
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- Cornillet, Martin (författare)
- Department of Medicine Huddinge, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden,Karolinska Univ Hosp, Karolinska Inst, Ctr Infect Med, Dept Med Huddinge, Stockholm, Sweden.
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- Nyhlin, Nils, 1971- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Örebro Univ, Fac Med & Hlth, Dept Gastroenterol, Örebro, Sweden.
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- Martin, Harry (författare)
- Department of Gastroenterology, University College Hospitals NHS Foundation Trust, London, United Kingdom,Univ Coll Hosp NHS Fdn Trust, Dept Gastroenterol, London, England.
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- Kechagias, Stergios, 1969- (författare)
- Linköping University,Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Mag- tarmmedicinska kliniken,Linköping Univ, Dept Hlth Med & Caring Sci, Unit Internal Med, Linköping, Sweden.
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- Wiencke, Kristine (författare)
- Norwegian PSC Research Centre, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway,Oslo Univ Hosp, Norwegian PSC Res Ctr, Div Surg Inflammatory Dis & Transplantat, Rikshosp,Dept Transplantat Med, Oslo, Norway.,Norwegian Radium Hospital
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- Werner, Mårten (författare)
- Umeå University,Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden.
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- Terziroli Beretta-Piccoli, Benedetta (författare)
- Epatocentro Ticino, Università della Svizzera Italiana, Lugano, Switzerland,Univ Svizzera Italiana, Epatocentro Ticino, Lugano, Switzerland.
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- Marzioni, Marco (författare)
- Clinic of Gastroenterology and Hepatology, Università Politecnica delle Marche, Ospedali Riuniti - University Hospital, Ancona, Italy,Univ Politecn Marche, Univ Hosp, Clin Gastroenterol & Hepatol, Ospedali Riuniti, Ancona, Italy.,Marche Polytechnic University
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- Isoniemi, Helena (författare)
- Transplantation and Liver Surgery, Abdominal Center, Helsinki University Hospital, Helsinki, Finland,Helsinki Univ Hosp, Abdominal Ctr, Transplantat & Liver Surg, Helsinki, Finland.,Helsinki University Central Hospital
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- Arola, Johanna (författare)
- Department of Pathology and Huslab, University of Helsinki and Helsinki University Hospital, Helsinki, Finland,Univ Helsinki, Helsinki Univ Hosp, Dept Pathol & Huslab, Helsinki, Finland.
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- Wefer, Agnes (författare)
- Division of Surgery, Karolinska University Hospital, Stockholm, Sweden,Karolinska Univ Hosp, Div Surg, Stockholm, Sweden.
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- Söderling, Jonas (författare)
- Karolinska Institute,Karolinska Institutet
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- Färkkilä, Martti (författare)
- University of Helsinki and Helsinki University Hospital, Clinic of Gastroenterology, Abdominal Center, Helsinki, Finland,Univ Helsinki, Abdominal Ctr, Clin Gastroenterol, Helsinki, Finland.;Helsinki Univ Hosp, Helsinki, Finland.
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- Lenzen, Henrike (författare)
- Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany; European Reference Network for Hepatological Diseases, Hannover, Germany; Department of Gastroenterology and Hepatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany,Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, Hannover, Germany.;European Reference Network Hepatol Dis, Hannover, Germany.;Univ Duisburg, Univ Hosp Essen, Dept Gastroenterol & Hepatol, Essen, Germany.
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(creator_code:org_t)
- 2022-05-16
- 2023
- Engelska.
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Ingår i: Liver international (Print). - Chichester, United Kingdom : Wiley-Blackwell Publishing Inc.. - 1478-3223 .- 1478-3231. ; 43:1, s. 127-138
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://liu.diva-por... (primary) (Raw object)
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https://uu.diva-port... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- BACKGROUND & AIMS: Evidence for the benefit of scheduled imaging for early detection of hepatobiliary malignancies in primary sclerosing cholangitis (PSC) is limited. We aimed to compare different follow-up strategies in PSC with the hypothesis that regular imaging improves survival.METHODS: We collected retrospective data from 2,975 PSC patients from 27 centers. Patients were followed from the start of scheduled imaging or in case of clinical follow-up from January 1, 2000, until death or last clinical follow-up alive. The primary endpoint was all-cause mortality.RESULTS: A broad variety of different follow-up strategies were reported. All except one center used regular imaging, ultrasound (US) and/or magnetic resonance imaging (MRI). Two centers used scheduled ERCP in addition to imaging for surveillance purposes. The overall HR (CI95%) for death, adjusted for sex, age and start year of follow-up, were 0.61 (0.47-0.80) for scheduled imaging with and without ERCP; 0.64 (0.48-0.86) for US/MRI and 0.53 (0.37-0.75) for follow-up strategies including scheduled ERCP. The lower risk of death remained for scheduled imaging with and without ERCP after adjustment for cholangiocarcinoma (CCA) or high-grade dysplasia as a time-dependent covariate, HR 0.57 (0.44-0.75). Hepatobiliary malignancy was diagnosed in 175 (5.9%) of the patients at 7.9 years follow-up. Asymptomatic patients (25%) with CCA had better survival if scheduled imaging had been performed.CONCLUSIONS: Follow-up strategies vary considerably across centers. Scheduled imaging was associated with improved survival. Multiple factors may contribute to this result including early tumor detection and increased endoscopic treatment of asymptomatic benign biliary strictures.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Annan klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Other Clinical Medicine (hsv//eng)
Nyckelord
- ERCP
- MRI
- cholangiocarcinoma
- follow-up strategy
- primary sclerosing cholangitis
- surveillance
- cholangiocarcinoma
- ERCP
- follow-up strategy
- MRI
- primary sclerosing cholangitis
- surveillance
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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- Av författaren/redakt...
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Bergquist, Annik ...
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Weismüller, Tobi ...
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Levy, Cynthia
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Rupp, Christian
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Joshi, Deepak
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Nayagam, Jeremy ...
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visa fler...
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Montano-Loza, Al ...
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Lytvyak, Ellina
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Wunsch, Ewa
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Milkiewicz, Piot ...
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Zenouzi, Roman
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Schramm, Christo ...
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Cazzagon, Nora
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Floreani, Annaro ...
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Friis Liby, Inga ...
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Wiestler, Miriam
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Wedemeyer, Heine ...
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Zhou, Taotao
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Strassburg, Chri ...
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Rigopoulou, Eiri ...
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Dalekos, George
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Narasimman, Mana ...
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Verhelst, Xavier
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Degroote, Helena
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Vesterhus, Mette
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Kremer, Andreas ...
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Bündgens, Bennet
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Rorsman, Fredrik ...
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Nilsson, Emma
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Jørgensen, Krist ...
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von Seth, Erik
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Cornillet, Marti ...
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Nyhlin, Nils, 19 ...
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Martin, Harry
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Kechagias, Sterg ...
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Wiencke, Kristin ...
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Werner, Mårten
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Terziroli Berett ...
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Marzioni, Marco
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Isoniemi, Helena
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Arola, Johanna
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Wefer, Agnes
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Söderling, Jonas
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Färkkilä, Martti
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Lenzen, Henrike
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Gastroenterologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Annan klinisk me ...
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Liver internatio ...
- Av lärosätet
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Örebro universitet
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Umeå universitet
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Linköpings universitet
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Uppsala universitet
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Karolinska Institutet
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Lunds universitet