Analytical partitioning of poly(ethyleneglycol)-modified proteins

• Covalently grafting proteins with varying numbers (n) of poly(ethylene glycol) molecules (PEGs) often enhances their biomedical and industrial usefulness. Partition between the phases in aqueous polymer two-phase systems can be used to rapidly characterize polymer-protein conjugates in a manner related to various enhancements. The logarithm of the partition coefficient (K) approximates linearity over the range 0

Nyckelord

Partitioning

aqueos two-phase systems

poly(ethylene glycol)

proteins

immunoglobulin

bovine serum albumin

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art (ämneskategori)