Animal botulism outcomes in the ani bio threat project

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Botulism disease in both humans and animals is a worldwide concern. Botulinum neurotoxins produced by Clostridium botulinum and other Clostridium species are the most potent biological substances known and are responsible for flaccid paralysis leading to a high mortality rate. Clostridium botulinum and botulinum neurotoxins are considered potential weapons for bioterrorism and have been included in the Australia Group List of Biological Agents. In 2010 the European Commission (DG Justice, Freedom and Security) funded a 3-year project named AniBioThreat to improve the EU's capacity to counter animal bioterrorism threats. A detection portfolio with screening methods for botulism agents and incidents was needed to improve tracking and tracing of accidental and deliberate contamination of the feed and food chain with botulinum neurotoxins and other Clostridia. The complexity of this threat required acquiring new genetic information to better understand the diversity of these Clostridia and develop detection methods targeting both highly specific genetic markers of these Clostridia and the neurotoxins they are able to produce. Several European institutes participating in the AniBioThreat project collaborated on this program to achieve these objectives. Their scientific developments are discussed here. © 2013, Mary Ann Liebert, Inc.

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Public Health, Global Health, Social Medicine and Epidemiology hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Arbetsmedicin och miljömedicin hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Occupational Health and Environmental Health hsv//eng
botulinum toxin
proteinase
agriculture
animal
animal disease
animal food
article
biological warfare
botulism
Clostridium botulinum
DNA fingerprinting
DNA sequence
food chain
genetics
isolation and purification
mass spectrometry
microbiology
real time polymerase chain reaction
Animal Diseases
Animal Feed
Animals
Bioterrorism
Botulinum Toxins
Endopeptidases
Real-Time Polymerase Chain Reaction
Sequence Analysis
DNA

Tevell Åberg, A. (author)
Skarin, HannaSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Inst för biomedicin och veterinär folkhälsovetenskap,Department of Biomedical Science and Veterinary Public Health(Swepub:slu)50655 (author)
Anniballi, F. (author)
De Medici, D. (author)
Bano, L. (author)
Koene, M. (author)
Löfström, CharlottaDTU Technical University of Denmark, Denmark(Swepub:ri)charlotta.lofstrom@ri.se (author)
Hansen, T. (author)
Hedeland, M. (author)
Fach, P. (author)
Sveriges lantbruksuniversitetInst för biomedicin och veterinär folkhälsovetenskap (creator_code:org_t)
Sveriges lantbruksuniversitet

In:Biosecurity and bioterrorism: Mary Ann Liebert Inc11:SUPPL. 1, s. S177-S1821538-71351557-850X

By the author/editor: Woudstra, C.; Tevell Åberg, A.; Skarin, Hanna; Anniballi, F.; De Medici, D.; Bano, L.; show more...; Koene, M.; Löfström, Charlo ...; Hansen, T.; Hedeland, M.; Fach, P.; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Public Health Gl ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Occupational Hea ...

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