Sökning: L773:1438 7492 OR L773:1439 2054 >
Monitoring DNA Hybr...
Monitoring DNA Hybridization with Organic Electrochemical Transistors Functionalized with Polydopamine
-
- Sensi, Matteo (författare)
- Università di Modena e Reggio Emilia, Italy
-
- Migatti, Giulio (författare)
- Università di Modena e Reggio Emilia, Italy
-
- Beni, Valerio, 1972- (författare)
- RISE,Smart hårdvara
-
visa fler...
-
- D'Alvise, Tommaso (författare)
- Max Planck Institute, Germany
-
- Weil, Tanja (författare)
- Max Planck Institute, Germany
-
- Berto, Marcello (författare)
- Università di Modena e Reggio Emilia, Italy
-
- Greco, Pierpalo (författare)
- Università di Modena e Reggio Emilia, Italy; Center for Translational Neurophysiology-Istituto Italiano di Tecnologia,, Italy
-
- Imbriano, Carol (författare)
- Università di Modena e Reggio Emilia, Italy
-
- Biscarini, Fabio (författare)
- Università di Modena e Reggio Emilia, Italy; Center for Translational Neurophysiology-Istituto Italiano di Tecnologia, Italy
-
- Bortolotti, Carlo (författare)
- Università di Modena e Reggio Emilia, Italy
-
visa färre...
-
(creator_code:org_t)
- 2022-02-10
- 2022
- Engelska.
-
Ingår i: Macromolecular materials and engineering. - : John Wiley and Sons Inc. - 1438-7492 .- 1439-2054. ; 307:5
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://onlinelibrar...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Organic electrochemical transistors (OECTs) are finding widespread application in biosensing, thanks to their high sensitivity, broad dynamic range, and low limit of detection. An OECT biosensor requires the immobilization of a biorecognition probe on the gate, or else on the channel, through several, often lengthy, chemical steps. In this work, a fast and straightforward way to functionalize the carbon gate of a fully screen-printed OECT by means of a polydopamine (PDA) film is presented. By chemical immobilization of an amine-terminated single-stranded oligonucleotide, containing the HSP70 promoter CCAAT sequence, on the PDA film, the detection of the complementary DNA strand is demonstrated. Furthermore, the specificity of the developed genosensor is assessed by comparing its response to the fully complementary strand with the one to partially complementary and noncomplementary oligonucleotides. The developed sensor shows a theoretical limit of detection (LOD) of 100 × 10−15 m and a dynamic range over four orders of magnitude. © 2022 The Authors.
Ämnesord
- TEKNIK OCH TEKNOLOGIER -- Elektroteknik och elektronik -- Annan elektroteknik och elektronik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Electrical Engineering, Electronic Engineering, Information Engineering -- Other Electrical Engineering, Electronic Engineering, Information Engineering (hsv//eng)
Nyckelord
- genosensors
- OECTs
- organic electronics
- polydopamine
- Chemical detection
- Transistors
- Biosensing
- DNA hybridization
- Dynamic range limits
- Functionalized
- High sensitivity
- Lower limits of detections
- Organic electrochemical transistors
- Oligonucleotides
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Sensi, Matteo
-
Migatti, Giulio
-
Beni, Valerio, 1 ...
-
D'Alvise, Tommas ...
-
Weil, Tanja
-
Berto, Marcello
-
visa fler...
-
Greco, Pierpalo
-
Imbriano, Carol
-
Biscarini, Fabio
-
Bortolotti, Carl ...
-
visa färre...
- Om ämnet
-
- TEKNIK OCH TEKNOLOGIER
-
TEKNIK OCH TEKNO ...
-
och Elektroteknik oc ...
-
och Annan elektrotek ...
- Artiklar i publikationen
-
Macromolecular m ...
- Av lärosätet
-
RISE