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- Matougui, NadaInserm, France (author)
Lipid-based nanoformulations for peptide delivery
- Article/chapterEnglish2016
Publisher, publication year, extent ...
- Elsevier,2016
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:ri-90
- https://urn.kb.se/resolve?urn=urn:nbn:se:ri:diva-90URI
- https://doi.org/10.1016/j.ijpharm.2016.02.019DOI
Supplementary language notes
- Language:English
- Summary in:English
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- SwePubSwePub
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Notes
- Nanoformulations have attracted a lot of attention because of their size-dependent properties. Among the array of nanoformulations, lipid nanoformulations (LNFs) have evoked increasing interest because of the advantages of their high degree of biocompatibility and versatility. The performance of lipid nanoformulations is greatly influenced by their composition and structure. Therapeutic peptides represent a growing share of the pharmaceutical market. However, the main challenge for their development into commercial products is their inherent physicochemical and biological instability. Important peptides such as insulin, calcitonin and cyclosporin A have been incorporated into LNFs. The association or encapsulation of peptides within lipid-based carriers has shown to protect the labile molecules against enzymatic degradation. This review describes strategies used for the formulation of peptides and some methods used for the assessment of association efficiency. The advantages and drawbacks of such carriers are also described.
Subject headings and genre
- NATURVETENSKAP Kemi Annan kemi hsv//swe
- NATURAL SCIENCES Chemical Sciences Other Chemistry Topics hsv//eng
- NATURVETENSKAP Kemi Fysikalisk kemi hsv//swe
- NATURAL SCIENCES Chemical Sciences Physical Chemistry hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Farmaceutiska vetenskaper hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Pharmaceutical Sciences hsv//eng
- Drug delivery
- Lipids
- Nanoformulations
- Peptides
Added entries (persons, corporate bodies, meetings, titles ...)
- Boge, LukasRISE,Life Science(Swepub:ri)lukas.boge@ri.se (author)
- Groo, Anne-ClaireInserm, France (author)
- Umerska, AnitaInserm, France (author)
- Ringstad, LovisaRISE,Life Science (author)
- Bysell, HelenaRISE,Life Science(Swepub:ri)helena.bysell@ri.se (author)
- Saulnier, PatrickInserm, France; CHU Angers, France (author)
- Inserm, FranceLife Science (creator_code:org_t)
Related titles
- In:International Journal of Pharmaceutics: Elsevier502:1-2, s. 80-970378-51731873-3476
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