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Spatiotemporal Feat...
Spatiotemporal Features of Neurogenesis in the Retina of Medaka, Oryzias latipes
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- Kitambi, Satish S. (författare)
- Södertörns högskola,Institutionen för livsvetenskaper,Karolinska Institutet / Harvard Medical School/MEEI, Boston, Massachusetts, USA
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- Malicki, Jarema J. (författare)
- Harvard Medical School/MEEI, Boston, Massachusetts, USA
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(creator_code:org_t)
- Wiley, 2008
- 2008
- Engelska.
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Ingår i: Developmental Dynamics. - : Wiley. - 1058-8388 .- 1097-0177. ; 237:12, s. 3870-3881
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Abstract
Ämnesord
Stäng
- The vertebrate retina is very well conserved in evolution. Its structure and functional features are very similar in phyla as different as primates and teleost fish. Here, we describe the spatiotemporal characteristics of neurogenesis in the retina of a teleost, medaka, and compare them with other species, primarily the zebrafish. Several intriguing differences are observed between medaka and zebrafish. For example, photoreceptor differentiation in the medaka retina starts independently in two different areas, and at more advanced stages of differentiation, medaka and zebrafish retinae display obviously different patterns of the photoreceptor cell mosaic. Medaka and zebrafish evolutionary lineages are thought to have separated from each other 110 million years ago, and so the differences between these species are not unexpected, and may be exploited to gain insight into the architecture of developmental pathways. Importantly, this work highlights the benefits of using multiple teleost models in parallel to understand a developmental process.
Ämnesord
- NATURVETENSKAP -- Biologi -- Utvecklingsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Developmental Biology (hsv//eng)
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- ref (ämneskategori)
- art (ämneskategori)
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