id:"swepub:oai:DiVA.org:sh-15847"
Search: id:"swepub:oai:DiVA.org:sh-15847" > Crystallization and...
- 1 of 1
- Previous record
- Next record
- To hitlist
- Meining, WinfriedSödertörns högskola,Avdelning Naturvetenskap (author)
Crystallization and preliminary crystallographic analysis of the recombinant N-terminal domain of riboflavin synthase
- Article/chapterEnglish2001
Publisher, publication year, extent ...
- 2001
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:sh-15847
- https://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-15847URI
- https://doi.org/10.1107/S0907444901010253DOI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:1961678URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Riboflavin synthase catalyzes the final step in the biosynthesis of riboflavin. Animals and humans lack this enzyme, whereas many bacteria and certain yeasts are absolutely dependent on endogenous riboflavin synthesis. Riboflavin synthase is therefore an attractive target for chemotherapy. The N-terminal domain of riboflavin synthase forms a dimer in solution and is capable of strongly binding riboflavin. It can serve as a model for the binding site of the native enzyme. Structural information obtained from this domain at high resolution will be helpful in the determination of the binding mode of riboflavin and thus for the development of antimicrobial drugs. Here, the crystallization and preliminary crystallographic analysis of the N-terminal domain of riboflavin synthase are reported. The crystals belong to the space group C222(1), with unit-cell parameters a = 50.3, b = 104.7, c = 85.3 Angstrom, alpha = beta = gamma = 90 degrees, and diffract to 2.6 Angstrom resolution.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
- Eberhardt, S (author)
- Bacher, A (author)
- Ladenstein, RKarolinska Institutet (author)
- Södertörns högskolaAvdelning Naturvetenskap (creator_code:org_t)
Related titles
- In:Acta Crystallographica Section D57, s. 1296-12990907-44491399-0047
Internet link
Find in a library
- Acta Crystallographica Section D (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Meining, Winfrie ...
- Eberhardt, S
- Bacher, A
- Ladenstein, R
- About the subject
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Biological Scien ...
- and Biochemistry and ...
- Articles in the publication
- Acta Crystallogr ...
- By the university
- Södertörn University
- Karolinska Institutet
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
