Sökning: (WFRF:(Zhang Y)) lar1:(sh)
> (2003-2004) >
Psychological burde...
-
Shor-Posner, G.Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
(författare)
Psychological burden in the era of Haart : Impact of selenium therapy
- Artikel/kapitelEngelska2003
Förlag, utgivningsår, omfång ...
-
Sage Publications,2003
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:sh-45214
-
https://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-45214URI
-
https://doi.org/10.2190/PFFD-D920-V041-N5KDDOI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-27956URI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
Objective: To determine the impact of nutritional (selenium) chemoprevention on levels of psychological burden (anxiety, depression, and mood state) in HIV/AIDS. Method: A randomized, double-blind, placebo-controlled selenium therapy (200 mug/day) trial was conducted in HIV+ drug users from 1998-2000. Psychosocial measures (STAI-State and Trait anxiety, BDI-depression, and POMS- mood state), clinical status (CD4 cell count, viral load), and plasma selenium levels were determined at baseline and compared with measurements obtained at the 12-month evaluation in 63 participants (32 men, 31 women). Results: The majority of the study participants reported elevated levels of both State (68%) and Trait (70%) anxiety. Approximately 25% reported overall mood distress (POMS > 60) and moderate depression (BDI > 20). Psychological burden was not influenced by current drug use, antiretroviral treatment, or viral load. At the 12-month evaluation, participants who received selenium reported increased vigor (p = 0.004) and had less anxiety (State, p = 0.05 and Trait, p = 0.02), compared to the placebo-treated individuals. No apparent selenium-related affect on depression or distress was observed. The risk for state anxiety was almost four times higher, and nearly nine times greater for trait anxiety in the placebo-treated group, controlling for antiretroviral therapy, CD4 cell decline (> 50 cells) and years of education. Conclusions: Selenium therapy may be a beneficial treatment to decrease anxiety in HIV+ drug users who exhibit a high prevalence of psychological burden.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Lecusay, Robert,1974-Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States(Swepub:hj)lecrob
(författare)
-
Miguez, M. J.Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
(författare)
-
Moreno-Black, G.Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
(författare)
-
Zhang, G. Y.Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
(författare)
-
Rodriguez, N.Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
(författare)
-
Burbano, X.Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
(författare)
-
Baum, M.Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
(författare)
-
Wilkie, F.Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
(författare)
-
Dept. of Psychiat./Behav. Sci. (D21), Division of Disease Prevention, Miami, United States
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:International Journal of Psychiatry in Medicine: Sage Publications33:1, s. 55-690091-21741541-3527
Internetlänk
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Shor-Posner, G.
-
Lecusay, Robert, ...
-
Miguez, M. J.
-
Moreno-Black, G.
-
Zhang, G. Y.
-
Rodriguez, N.
-
visa fler...
-
Burbano, X.
-
Baum, M.
-
Wilkie, F.
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Psykiatri
- Artiklar i publikationen
-
International Jo ...
- Av lärosätet
-
Södertörns högskola
-
Jönköping University