Search: id:"swepub:oai:DiVA.org:su-158192" >
Perfluoroalkyl Acid...
-
Gyllenhammar, Irina
(author)
Perfluoroalkyl Acids (PFAAs) in Serum from 2-4-Month-Old Infants : Influence of Maternal Serum Concentration, Gestational Age, Breast-Feeding, and Contaminated Drinking Water
- Article/chapterEnglish2018
Publisher, publication year, extent ...
-
2018-05-15
-
American Chemical Society (ACS),2018
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:su-158192
-
https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-158192URI
-
https://doi.org/10.1021/acs.est.8b00770DOI
-
https://res.slu.se/id/publ/95937URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Little is known about factors influencing infant perfluorinated alkyl acid (PFAA) concentrations. Associations between serum PFAA concentrations in 2-4-month-old infants (n = 101) and determinants were investigated by multiple linear regression and general linear model analysis. In exclusively breastfed infants, maternal serum PFAA concentrations 3 weeks after delivery explained 13% (perfluoroundecanoic acid, PFUnDA) to 73% (perfluorohexanesulfonate, PFHxS) of infant PFAA concentration variation. Median infant/maternal ratios decreased with increasing PFAA carbon chain length from 2.8 for perfluoroheptanoic acid and perfluorooctanoic acid (PFOA) to 0.53 for PFUnDA and from 1.2 to 0.69 for PFHxS and perfluorooctanesulfonate (PFOS). Infant PFOA, perfluorononanoic acid (PFNA), and PFOS levels increased 0.7-1.2% per day of gestational age. Bottle-fed infants had mean concentrations of PFAAs 2 times lower than and a mean percentage of branched (%br) PFOS isomers 1.3 times higher than those of exclusively breast-fed infants. PFOA, PFNA, and PFHxS levels increased 8-11% per week of exclusive breast-feeding. Infants living in an area receiving PFAA-contaminated drinking water had 3-fold higher mean perfluorobutanesulfonate (PFBS) and PFHxS concentrations and higher mean %br PFHxS. Prenatal PFAA exposure and postnatal PFAA exposure significantly contribute to infant PFAA serum concentrations, depending on PFAA carbon chain length. Moderately PFBS- and PFHxS-contaminated drinking water is an important indirect exposure source.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Benskin, Jonathan P.Stockholms universitet,Institutionen för miljövetenskap och analytisk kemi(Swepub:su)jbens
(author)
-
Sandblom, OskarStockholms universitet,Institutionen för miljövetenskap och analytisk kemi(Swepub:su)ossa1616
(author)
-
Berger, Urs
(author)
-
Ahrens, LutzSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för vatten och miljö,Department of Aquatic Sciences and Assessment(Swepub:slu)50142
(author)
-
Lignell, Sanna
(author)
-
Wiberg, KarinSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för vatten och miljö,Department of Aquatic Sciences and Assessment(Swepub:slu)48881
(author)
-
Glynn, AndersSwedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Inst för biomedicin och veterinär folkhälsovetenskap,Department of Biomedical Science and Veterinary Public Health,National Food Agency
(author)
-
Stockholms universitetInstitutionen för miljövetenskap och analytisk kemi
(creator_code:org_t)
-
Sveriges lantbruksuniversitet
Related titles
-
In:Environmental Science and Technology: American Chemical Society (ACS)52:12, s. 7101-71100013-936X1520-5851
Internet link
Find in a library
To the university's database