More severe intellectual disability found in teenagers compared to younger children with Down syndrome

Wester Oxelgren, Ulrika,1960-Uppsala universitet,Institutionen för kvinnors och barns hälsa,pediatrisk inflammations- och metabolismforskning samt barnhälsa (author)

Aim: We investigated the severities and profiles of intellectual disability (ID) in a population-based group of children with Down syndrome and related the findings to coexisting autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD).Methods: There were about 100 children with Down syndrome living in Uppsala County, Sweden, at the time of the study who all received medical services from the same specialist outpatient clinic. The 60 children (68% male) were aged 5-17 years at inclusion: 41 were assessed within the study and 19 had test results from previous assessments, performed within three years before inclusion. We compared two age groups: 5-12 and 13-18 years old.Results: Of the 60 children, 49 were assessed with a cognitive test and the 11 children who could not participate in formal tests had clinical assessments. Mild ID was found in 9% of the older children and in 35% of the younger children. Severe ID was found in 91% of the older children and 65% of the younger children. Verbal and nonverbal domains did not differ.Conclusion: Intellectual level was lower in the older children and patients with Down syndrome need to be followed during childhood with regard to their ID levels.

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Pediatrik hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Pediatrics hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Psykiatri hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Psychiatry hsv//eng
attention deficit hyperactivity disorder
autism spectrum disorder
cognitive profile
Down syndrome
intellectual disability
Psychology
psykologi
Attention deficit hyperactivity disorder; Autism spectrum disorder; Cognitive profile; Down syndrome; Intellectual disability

Myrelid, Åsa,1974-Uppsala universitet,Institutionen för kvinnors och barns hälsa,pediatrisk inflammations- och metabolismforskning samt barnhälsa(Swepub:uu)asmyr424 (author)
Annerén, Göran,1945-Uppsala universitet,Medicinsk genetik och genomik(Swepub:uu)goraanne (author)
Westerlund, JoakimGöteborgs universitet,Stockholms universitet,Kognitiv psykologi,Gothenburg University, Sweden,Gillbergcentrum,Gillberg Neuropsychiatry Centre(Swepub:su)jwest (author)
Gustafsson, Jan,1948-Uppsala universitet,Institutionen för kvinnors och barns hälsa,pediatrisk inflammations- och metabolismforskning samt barnhälsa(Swepub:uu)jangfs (author)
Fernell, Elisabeth,1948Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre(Swepub:gu)xferne (author)
Uppsala universitetInstitutionen för kvinnors och barns hälsa (creator_code:org_t)

By the author/editor: Wester Oxelgren, ...; Myrelid, Åsa, 19 ...; Annerén, Göran, ...; Westerlund, Joak ...; Gustafsson, Jan, ...; Fernell, Elisabe ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Pediatrics

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Psychiatry

By the university: Stockholm University; Uppsala University; University of Gothenburg

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