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Is There an Associa...
Is There an Association Between Ambient Air Pollution and Bladder Cancer Incidence? Analysis of 15 European Cohorts
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Pedersen, Marie (author)
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Stafoggia, Massimo (author)
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Weinmayr, Gudrun (author)
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show more...
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Andersen, Zorana J. (author)
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Galassi, Claudia (author)
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- Sommar, Johan (author)
- Umeå universitet,Yrkes- och miljömedicin
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- Forsberg, Bertil (author)
- Umeå universitet,Yrkes- och miljömedicin
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- Olsson, David (author)
- Umeå universitet,Yrkes- och miljömedicin
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Oftedal, Bente (author)
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Krog, Norun H. (author)
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Aamodt, Geir (author)
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- Pyko, Andrei (author)
- Karolinska Institutet
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- Pershagen, Goran (author)
- Karolinska Institutet
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Korek, Michal (author)
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- De Faire, Ulf (author)
- Karolinska Institutet
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- Pedersen, Nancy L. (author)
- Karolinska Institutet
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Odiaeresi, Claes-Goran (author)
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- Fratiglioni, Laura (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
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Sorensen, Mette (author)
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Eriksen, Kirsten T. (author)
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Tjonneland, Anne (author)
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Peeters, Petra H. (author)
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Bueno-de-Mesquita, Bas (author)
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Vermeulen, Roel (author)
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Eeftens, Marloes (author)
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Plusquin, Michelle (author)
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Key, Timothy J. (author)
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Jaensch, Andrea (author)
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Nagel, Gabriele (author)
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Concin, Hans (author)
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Wang, Meng (author)
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Tsai, Ming-Yi (author)
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Grioni, Sara (author)
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Marcon, Alessandro (author)
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Krogh, Vittorio (author)
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Ricceri, Fulvio (author)
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Sacerdote, Carlotta (author)
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Ranzi, Andrea (author)
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Cesaroni, Giulia (author)
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Forastiere, Francesco (author)
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Tamayo, Ibon (author)
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Amiano, Pilar (author)
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Dorronsoro, Miren (author)
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Stayner, Leslie T. (author)
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Kogevinas, Manolis (author)
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Nieuwenhuijsen, Mark J. (author)
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Sokhi, Ranjeet (author)
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de Hoogh, Kees (author)
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Beelen, Rob (author)
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Vineis, Paolo (author)
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Brunekreef, Bert (author)
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Hoek, Gerard (author)
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Raaschou-Nielsen, Ole (author)
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Östenson, Claes-Göran (author)
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(creator_code:org_t)
- Elsevier BV, 2018
- 2018
- English.
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In: European Urology Focus. - : Elsevier BV. - 2405-4569. ; 4:1, s. 113-120
- Related links:
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https://iris.unito.i...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Subject headings
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- Background: Ambient air pollution contains low concentrations of carcinogens implicated in the etiology of urinary bladder cancer (BC). Little is known about whether exposure to air pollution influences BC in the general population. Objective: To evaluate the association between long-term exposure to ambient air pollution and BC incidence. Design, setting and participants: We obtained data from 15 population-based cohorts enrolled between 1985 and 2005 in eight European countries (N = 303 431; mean follow-up 14.1 yr). We estimated exposure to nitrogen oxides (NO2 and NOx), particulate matter (PM) with diameter <10 mu m (PM10), <2.5 mu m (PM2.5). between 2.5 and 10 mu m (PM2.5-10). PM2.5 absorbance (soot), elemental constituents of PM, organic carbon, and traffic density at baseline home addresses using standardized land-use regression models from the European Study of Cohorts for Air Pollution Effects project. Outcome measurements and statistical analysis: We used Cox proportional-hazards models with adjustment for potential confounders for cohort-specific analyses and meta-analyses to estimate summary hazard ratios (HRS) for BC incidence. Results and limitations: During follow-up, 943 incident BC cases were diagnosed. In the meta-analysis, none of the exposures were associated with BC risk. The summary HRs associated with a 10-mu g/m(3) increase in NO2 and 51-mu g/m(3) increase in PM2.5 were 0.98 (95% confidence interval [CI] 0.89-1.08) and 0.86 (95% CI 0.63-1.18), respectively. Limitations include the lack of information about lifetime exposure. Conclusions: There was no evidence of an association between exposure to outdoor air pollution levels at place of residence and risk of BC. Patient summary: We assessed the link between outdoor air pollution at place of residence and bladder cancer using the largest study population to date and extensive assessment of exposure and comprehensive data on personal risk factors such as smoking. We found no association between the levels of outdoor air pollution at place of residence and bladder cancer risk.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Keyword
- Air pollution
- Bladder cancer
- Environment
- Prevention
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Pedersen, Marie
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Stafoggia, Massi ...
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Weinmayr, Gudrun
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Andersen, Zorana ...
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Galassi, Claudia
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Sommar, Johan
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show more...
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Forsberg, Bertil
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Olsson, David
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Oftedal, Bente
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Krog, Norun H.
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Aamodt, Geir
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Pyko, Andrei
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Pershagen, Goran
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Korek, Michal
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De Faire, Ulf
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Pedersen, Nancy ...
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Odiaeresi, Claes ...
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Fratiglioni, Lau ...
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Sorensen, Mette
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Eriksen, Kirsten ...
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Tjonneland, Anne
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Peeters, Petra H ...
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Bueno-de-Mesquit ...
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Vermeulen, Roel
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Eeftens, Marloes
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Plusquin, Michel ...
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Key, Timothy J.
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Jaensch, Andrea
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Nagel, Gabriele
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Concin, Hans
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Wang, Meng
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Tsai, Ming-Yi
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Grioni, Sara
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Marcon, Alessand ...
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Krogh, Vittorio
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Ricceri, Fulvio
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Sacerdote, Carlo ...
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Ranzi, Andrea
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Cesaroni, Giulia
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Forastiere, Fran ...
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Tamayo, Ibon
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Amiano, Pilar
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Dorronsoro, Mire ...
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Stayner, Leslie ...
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Kogevinas, Manol ...
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Nieuwenhuijsen, ...
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Sokhi, Ranjeet
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de Hoogh, Kees
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Beelen, Rob
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Vineis, Paolo
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Brunekreef, Bert
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Hoek, Gerard
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Raaschou-Nielsen ...
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Östenson, Claes- ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Urology and Neph ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Occupational Hea ...
- Articles in the publication
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European Urology ...
- By the university
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Stockholm University
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Umeå University
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Karolinska Institutet