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Laterality of deep ...
Laterality of deep white matter hyperintensities correlates with basilar artery bending and vertebral artery dominance
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- Szalontai, Laszlo (författare)
- Medical Imaging Centre, Semmelweis University, Budapest, Hungary
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- Jokkel, Zsofia (författare)
- Medical Imaging Centre, Semmelweis University, Budapest, Hungary
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- Horvath, Tamas (författare)
- Department of Hydrodynamic Systems, Budapest University of Technology and Economics, Budapest, Hungary
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- Forgo, Bianka, 1992- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Radiology
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- Kalina, Ildiko (författare)
- Medical Imaging Centre, Semmelweis University, Budapest, Hungary
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- Maurovich-Horvat, Pal (författare)
- Medical Imaging Centre, Semmelweis University, Budapest, Hungary
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- Auyang, Philip L. (författare)
- Department of Cardiovascular Surgery Methodist De Bakey Heart & Vascular Center, Houston Texas, USA
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- Zubair, M. Mujeeb (författare)
- Department of Cardiovascular Surgery Methodist De Bakey Heart & Vascular Center, Houston Texas, USA
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- Garami, Zsolt (författare)
- Department of Cardiovascular Surgery Methodist De Bakey Heart & Vascular Center, Houston Texas, USA
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- Tarnoki, David Laszlo (författare)
- Department of Radiology and Oncotherapy, Semmelweis University, Budapest, Hungary
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- Tarnoki, Adam Domonkos (författare)
- Department of Radiology and Oncotherapy, Semmelweis University, Budapest, Hungary
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(creator_code:org_t)
- Zagreb University School of Medicine, 2021
- 2021
- Engelska.
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Ingår i: Croatian Medical Journal. - : Zagreb University School of Medicine. - 0353-9504 .- 1332-8166. ; 62:4, s. 360-366
- Relaterad länk:
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https://doi.org/10.3...
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https://www.ncbi.nlm...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
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- Aim: To investigate whether vertebrobasilar geometry contributes to the presence, severity, and laterality of white matter hyperintensities (WMH).Methods: We retrospectively reviewed 290 cerebral scans of patients who underwent time-of-flight and fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) between 2017 and 2018. WMH were counted, localized, and grouped according to laterality on the FLAIR sequence. A 3D mesh of the posterior circulation was reconstructed (with ITK SNAP software) and the morphology of the vertebrobasilar system analyzed with an in-house software written in Python.Results: Patients were assigned into a group with WMH (n = 204) and a group without WMH (n = 86). The severity of WMH burden was mainly affected by age and hypertension, while the localization of the WMH (or laterality) was mainly affected by the vertebrobasilar system morphology. Basilar artery morphology only affected the parietooccipital region significantly if both posterior communicating arteries were hypoplastic or absent. The dominant vertebral artery and basilar artery curve had an opposite directional relationship.Conclusions: An unequal vertebral artery flow is an important hemodynamic contributor to basilar bending. Increased basilar artery curvature and increased infratentorial WMH burden may signal inadequate blood flow and predict cerebrovascular events.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
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Szalontai, Laszl ...
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Jokkel, Zsofia
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Horvath, Tamas
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Forgo, Bianka, 1 ...
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Kalina, Ildiko
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Maurovich-Horvat ...
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Auyang, Philip L ...
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Zubair, M. Mujee ...
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Garami, Zsolt
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Tarnoki, David L ...
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Tarnoki, Adam Do ...
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