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Search: (hsv:(SAMHÄLLSVETENSKAP)) lar1:(miun) lar1:(his) mspu:(article) pers:(Rahkonen Ossi) > (2020) > Association of Heal...

  • Nyberg, Solja T.Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland (author)

Association of Healthy Lifestyle With Years Lived Without Major Chronic Diseases

  • Article/chapterEnglish2020

Publisher, publication year, extent ...

  • American Medical Association (AMA),2020
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:su-183135
  • https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-183135URI
  • https://doi.org/10.1001/jamainternmed.2020.0618DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-171822URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-38964URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-18404URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:143724227URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • This cohort study examines disease-free life-years in participants with varying combinations of lifestyle risk factors.Question: Are different combinations of lifestyle factors associated with years lived without chronic diseases?Findings: In a multicohort study of 116 & x202f;043 participants, a statistically significant association between overall healthy lifestyle score and an increased number of disease-free life-years was noted. Of 16 different lifestyle profiles studied, the 4 that were associated with the greatest disease-free life years included body mass index lower than 25 and at least 2 of 3 factors: never smoking, physical activity, and moderate alcohol consumption.Meaning: Various healthy lifestyle profiles appear to be associated with extended gains in life lived without type 2 diabetes, cardiovascular and respiratory diseases, and cancer.Importance: It is well established that selected lifestyle factors are individually associated with lower risk of chronic diseases, but how combinations of these factors are associated with disease-free life-years is unknown.Objective: To estimate the association between healthy lifestyle and the number of disease-free life-years.Design, Setting, and Participants: A prospective multicohort study, including 12 European studies as part of the Individual-Participant-Data Meta-analysis in Working Populations Consortium, was performed. Participants included 116 & x202f;043 people free of major noncommunicable disease at baseline from August 7, 1991, to May 31, 2006. Data analysis was conducted from May 22, 2018, to January 21, 2020.Exposures: Four baseline lifestyle factors (smoking, body mass index, physical activity, and alcohol consumption) were each allocated a score based on risk status: optimal (2 points), intermediate (1 point), or poor (0 points) resulting in an aggregated lifestyle score ranging from 0 (worst) to 8 (best). Sixteen lifestyle profiles were constructed from combinations of these risk factors.Main Outcomes and Measures: The number of years between ages 40 and 75 years without chronic disease, including type 2 diabetes, coronary heart disease, stroke, cancer, asthma, and chronic obstructive pulmonary disease.Results: Of the 116 & x202f;043 people included in the analysis, the mean (SD) age was 43.7 (10.1) years and 70 & x202f;911 were women (61.1%). During 1.45 million person-years at risk (mean follow-up, 12.5 years; range, 4.9-18.6 years), 17 & x202f;383 participants developed at least 1 chronic disease. There was a linear association between overall healthy lifestyle score and the number of disease-free years, such that a 1-point improvement in the score was associated with an increase of 0.96 (95% CI, 0.83-1.08) disease-free years in men and 0.89 (95% CI, 0.75-1.02) years in women. Comparing the best lifestyle score with the worst lifestyle score was associated with 9.9 (95% CI 6.7-13.1) additional years without chronic diseases in men and 9.4 (95% CI 5.4-13.3) additional years in women (P < .001 for dose-response). All of the 4 lifestyle profiles that were associated with the highest number of disease-free years included a body-mass index less than 25 (calculated as weight in kilograms divided by height in meters squared) and at least 2 of the following factors: never smoking, physical activity, and moderate alcohol consumption. Participants with 1 of these lifestyle profiles reached age 70.3 (95% CI, 69.9-70.8) to 71.4 (95% CI, 70.9-72.0) years disease free depending on the profile and sex.Conclusions and Relevance: In this multicohort analysis, various healthy lifestyle profiles appeared to be associated with gains in life-years without major chronic diseases.

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  • Singh-Manoux, ArchanaDepartment of Epidemiology and Public Health, University College London, United Kingdom / Inserm U1153, Epidemiology of Ageing and Neurodegenrative Diseases, Paris, France (author)
  • Pentti, JaanaClinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland / Department of Public Health, University of Turku, Turku University Hospital, Finland / Centre for Population Health Research, University of Turku, Turku University Hospital, Finland (author)
  • Madsen, Ida E. H.National Research Centre for the Working Environment, Copenhagen, Denmark (author)
  • Sabia, SeverineDepartment of Epidemiology and Public Health, University College London, United Kingdom / Inserm U1153, Epidemiology of Ageing and Neurodegenrative Diseases, Paris, France (author)
  • Alfredsson, LarsKarolinska Institutet (author)
  • Bjorner, Jakob B.National Research Centre for the Working Environment, Copenhagen, Denmark (author)
  • Borritz, MarianneBispebjerg University Hospital, Copenhagen, Denmark (author)
  • Burr, HermannFederal Institute for Occupational Safety and Health, Berlin, Germany (author)
  • Goldberg, MarcelFaculty of Medicine, Paris Descartes University, Paris, France / Inserm UMS 011, Population-Based Epidemiological Cohorts Unit, Villejuif, France (author)
  • Heikkila, KatriinaDepartment of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, United Kingdom (author)
  • Jokela, MarkusDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland (author)
  • Knutsson, Anders,1942-Mittuniversitetet,Institutionen för hälsovetenskap,Department of Health Sciences, Mid Sweden University, Sundsvall, Sweden(Swepub:miun)andknu (author)
  • Lallukka, TeaClinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland / Finnish Institute of Occupational Health, Helsinki, Finland (author)
  • Lindbohm, JoniClinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland (author)
  • Nielsen, Martin L.AS3 Employment, AS3 Companies, Viby J, Denmark (author)
  • Nordin, MariaUmeå universitet,Stockholms universitet,Stressforskningsinstitutet,Stress Research Institute, Stockholm University, Sweden / Department of Psychology, Umeå University, Sweden,Institutionen för psykologi,Stress Research Institute, Stockholm University, Stockholm, Sweden(Swepub:umu)nonmaa98 (author)
  • Oksanen, TuulaFinnish Institute of Occupational Health, Helsinki, Finland (author)
  • Pejtersen, Jan H.VIVE-The Danish Center for Social Science Research, Copenhagen, Denmark (author)
  • Rahkonen, OssiClinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland (author)
  • Rugulies, ReinerNational Research Centre for the Working Environment, Copenhagen, Denmark / Department of Public Health, Department of Psychology, University of Copenhagen, Denmark (author)
  • Shipley, Martin J.Department of Epidemiology and Public Health, University College London, United Kingdom (author)
  • Sipila, Pyry N.Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland (author)
  • Stenholm, SariDepartment of Public Health, University of Turku, Turku University Hospital, Finland / Centre for Population Health Research, University of Turku, Turku University Hospital, Finland (author)
  • Suominen, SakariHögskolan i Skövde,Institutionen för hälsovetenskaper,Forskningsmiljön hälsa, hållbarhet och digitalisering,Department of Public Health, University of Turku, Turku University Hospital, Finland,Individ och samhälle (VIDSOC), Individual and society(Swepub:his)suos (author)
  • Vahtera, JussiDepartment of Public Health, University of Turku, Turku University Hospital, Finland / Centre for Population Health Research, University of Turku, Turku University Hospital, Finland (author)
  • Virtanen, MariannaKarolinska Institutet (author)
  • Westerlund, HugoKarolinska Institutet,Stockholms universitet,Stressforskningsinstitutet,Stress Research Institute, Stockholm University, Sweden(Swepub:su)hwest (author)
  • Zins, MarieFaculty of Medicine, Paris Descartes University, France / Inserm UMS 011, Population-Based Epidemiological Cohorts Unit, Villejuif, France (author)
  • Hamer, MarkDivision of Surgery and Interventional Science, Faculty of Medical Sciences, University College London, United Kingdom (author)
  • Batty, G. DavidDepartment of Epidemiology and Public Health, University College London, United Kingdom / School of Biological and Population Health Sciences, Oregon State University, Corvallis, OR, United States (author)
  • Kivimaki, MikaClinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, Finland / Department of Epidemiology and Public Health, University College London, United Kingdom (author)
  • Clinicum, Department of Public Health, Faculty of Medicine, University of Helsinki, FinlandDepartment of Epidemiology and Public Health, University College London, United Kingdom / Inserm U1153, Epidemiology of Ageing and Neurodegenrative Diseases, Paris, France (creator_code:org_t)

Related titles

  • In:JAMA Internal Medicine: American Medical Association (AMA)180:5, s. 760-7682168-61062168-6114

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