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Long-Term Exposure ...
Long-Term Exposure to Source-Specific Fine Particles and Mortality-A Pooled Analysis of 14 European Cohorts within the ELAPSE Project
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Chen, Jie (author)
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Hoek, Gerard (author)
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de Hoogh, Kees (author)
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show more...
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Rodopoulou, Sophia (author)
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Andersen, Zorana J. (author)
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- Bellander, Tom (author)
- Karolinska Institutet
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Brandt, Jørgen (author)
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Fecht, Daniela (author)
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Forastiere, Francesco (author)
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Gulliver, John (author)
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Hertel, Ole (author)
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Hoffmann, Barbara (author)
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Hvidtfeldt, Ulla Arthur (author)
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Verschuren, W. M. Monique (author)
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Jöckel, Karl-Heinz (author)
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Jrgensen, Jeanette T. (author)
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- Katsouyanni, Klea (author)
- Karolinska Institutet
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Ketzel, Matthias (author)
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- Méndez, Diego Yacamán (author)
- Karolinska Institutet
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Leander, Karin (author)
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Liu, Shuo (author)
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- Ljungman, Petter (author)
- Karolinska Institutet
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Faure, Elodie (author)
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Magnusson, Patrik K. E. (author)
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Nagel, Gabriele (author)
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- Pershagen, Göran (author)
- Karolinska Institutet
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Peters, Annette (author)
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Raaschou-Nielsen, Ole (author)
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- Rizzuto, Debora (author)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
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Samoli, Evangelia (author)
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van der Schouw, Yvonne T. (author)
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Schramm, Sara (author)
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Severi, Gianluca (author)
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Stafoggia, Massimo (author)
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Strak, Maciej (author)
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Sørensen, Mette (author)
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Tjønneland, Anne (author)
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Weinmayr, Gudrun (author)
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Wolf, Kathrin (author)
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Zitt, Emanuel (author)
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Brunekreef, Bert (author)
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Thurston, George D. (author)
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(creator_code:org_t)
- 2022-06-23
- 2022
- English.
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In: Environmental Science and Technology. - : American Chemical Society (ACS). - 0013-936X .- 1520-5851. ; 56:13, s. 9277-9290
- Related links:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Subject headings
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- We assessed mortality risks associated with sourcespecific fine particles (PM2.5) in a pooled European cohort of 323,782 participants. Cox proportional hazard models were applied to estimate mortality hazard ratios (HRs) for source-specific PM2.5 identified through a source apportionment analysis. Exposure to 2010 annual average concentrations of source-specific PM2.5 components was assessed at baseline residential addresses. The source apportionment resulted in the identification of five sources: traffic, residual oil combustion, soil, biomass and agriculture, and industry. In single-source analysis, all identified sources were significantly positively associated with increased natural mortality risks. In multisource analysis, associations with all sources attenuated but remained statistically significant with traffic, oil, and biomass and agriculture. The highest association per interquartile increase was observed for the traffic component (HR: 1.06; 95% CI: 1.04 and 1.08 per 2.86 mu g/m(3) increase) across five identified sources. On a 1 mu g/m(3) basis, the residual oil-related PM2.5 had the strongest association (HR: 1.13; 95% CI: 1.05 and 1.22), which was substantially higher than that for generic PM2.5 mass, suggesting that past estimates using the generic PM2.5 exposure response function have underestimated the potential clean air health benefits of reducing fossil-fuel combustion. Source-specific associations with cause-specific mortality were in general consistent with findings of natural mortality.
Subject headings
- NATURVETENSKAP -- Geovetenskap och miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Keyword
- source apportionment
- fine particulate matter (PM2.5)
- absolute principal component analysis (APCA)
- mortality
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Chen, Jie
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Hoek, Gerard
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de Hoogh, Kees
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Rodopoulou, Soph ...
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Andersen, Zorana ...
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Bellander, Tom
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show more...
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Brandt, Jørgen
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Fecht, Daniela
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Forastiere, Fran ...
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Gulliver, John
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Hertel, Ole
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Hoffmann, Barbar ...
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Hvidtfeldt, Ulla ...
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Verschuren, W. M ...
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Jöckel, Karl-Hei ...
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Jrgensen, Jeanet ...
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Katsouyanni, Kle ...
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Ketzel, Matthias
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Méndez, Diego Ya ...
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Leander, Karin
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Liu, Shuo
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Ljungman, Petter
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Faure, Elodie
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Magnusson, Patri ...
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Nagel, Gabriele
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Pershagen, Göran
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Peters, Annette
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Raaschou-Nielsen ...
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Rizzuto, Debora
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Samoli, Evangeli ...
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van der Schouw, ...
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Schramm, Sara
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Severi, Gianluca
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Stafoggia, Massi ...
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Strak, Maciej
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Sørensen, Mette
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Tjønneland, Anne
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Weinmayr, Gudrun
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Wolf, Kathrin
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Zitt, Emanuel
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Brunekreef, Bert
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Thurston, George ...
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Earth and Relate ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Occupational Hea ...
- Articles in the publication
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Environmental Sc ...
- By the university
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Stockholm University
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Karolinska Institutet