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Population genomics...
Population genomics of the muskox' resilience in the near absence of genetic variation
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Pečnerová, Patrícia (author)
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- Lord, Edana (author)
- Stockholms universitet,Zoologiska institutionen,Centre for Palaeogenetics, Sweden; Swedish Museum of Natural History, Sweden
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Garcia-Erill, Genís (author)
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Hanghøj, Kristian (author)
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Rasmussen, Malthe Sebro (author)
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Meisner, Jonas (author)
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Liu, Xiaodong (author)
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van der Valk, Tom (author)
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Santander, Cindy G. (author)
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Quinn, Liam (author)
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Lin, Long (author)
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Liu, Shanlin (author)
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Carøe, Christian (author)
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Dalerum, Fredrik (author)
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- Götherström, Anders, 1969- (author)
- Stockholms universitet,Arkeologiska forskningslaboratoriet,Centre for Palaeogenetics, Sweden
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- Måsviken, Johannes, 1990- (author)
- Stockholms universitet,Zoologiska institutionen,Centre for Palaeogenetics, Sweden; Swedish Museum of Natural History, Sweden
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Vartanyan, Sergey (author)
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Raundrup, Katrine (author)
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Al-Chaer, Amal (author)
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Rasmussen, Linett (author)
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Hvilsom, Christina (author)
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Heide-Jørgensen, Mads Peter (author)
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Sinding, Mikkel-Holger S. (author)
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Aastrup, Peter (author)
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Van Coeverden de Groot, Peter J. (author)
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Schmidt, Niels Martin (author)
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Albrechtsen, Anders (author)
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- Dalén, Love, 1980- (author)
- Stockholms universitet,Zoologiska institutionen,Centre for Palaeogenetics, Sweden; Swedish Museum of Natural History, Sweden
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Heller, Rasmus (author)
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Moltke, Ida (author)
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Redlef Siegismund, Hans (author)
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(creator_code:org_t)
- 2024
- 2024
- English.
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In: Molecular Ecology. - 0962-1083 .- 1365-294X. ; 33:2
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Genomic studies of species threatened by extinction are providing crucial information about evolutionary mechanisms and genetic consequences of population declines and bottlenecks. However, to understand how species avoid the extinction vortex, insights can be drawn by studying species that thrive despite past declines. Here, we studied the population genomics of the muskox (Ovibos moschatus), an Ice Age relict that was at the brink of extinction for thousands of years at the end of the Pleistocene yet appears to be thriving today. We analysed 108 whole genomes, including present-day individuals representing the current native range of both muskox subspecies, the white-faced and the barren-ground muskox (O. moschatus wardi and O. moschatus moschatus) and a ~21,000-year-old ancient individual from Siberia. We found that the muskox' demographic history was profoundly shaped by past climate changes and post-glacial re-colonizations. In particular, the white-faced muskox has the lowest genome-wide heterozygosity recorded in an ungulate. Yet, there is no evidence of inbreeding depression in native muskox populations. We hypothesize that this can be explained by the effect of long-term gradual population declines that allowed for purging of strongly deleterious mutations. This study provides insights into how species with a history of population bottlenecks, small population sizes and low genetic diversity survive against all odds.
Subject headings
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
Keyword
- ancient DNA
- genetic diversity
- genetic load
- inbreeding
- muskox
- population genomics
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Pečnerová, Patrí ...
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Lord, Edana
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Garcia-Erill, Ge ...
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Hanghøj, Kristia ...
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Rasmussen, Malth ...
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Meisner, Jonas
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show more...
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Liu, Xiaodong
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van der Valk, To ...
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Santander, Cindy ...
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Quinn, Liam
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Lin, Long
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Liu, Shanlin
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Carøe, Christian
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Dalerum, Fredrik
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Götherström, And ...
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Måsviken, Johann ...
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Vartanyan, Serge ...
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Raundrup, Katrin ...
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Al-Chaer, Amal
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Rasmussen, Linet ...
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Hvilsom, Christi ...
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Heide-Jørgensen, ...
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Sinding, Mikkel- ...
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Aastrup, Peter
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Van Coeverden de ...
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Schmidt, Niels M ...
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Albrechtsen, And ...
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Dalén, Love, 198 ...
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Heller, Rasmus
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Moltke, Ida
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Redlef Siegismun ...
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Evolutionary Bio ...
- Articles in the publication
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Molecular Ecolog ...
- By the university
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Stockholm University