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Maternal age and th...
Maternal age and the risk of low birthweight and pre-term delivery : a pan-Nordic comparison
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- Aradhya, Siddartha (author)
- Stockholm University,Stockholms universitet,Sociologiska institutionen,Lund University, Lund, Sweden
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- Tegunimataka, Anna (author)
- Lund University,Lunds universitet,Centrum för ekonomisk demografi,Ekonomihögskolan,Ekonomisk-historiska institutionen,LU profilområde: Mänskliga rättigheter,Lunds universitets profilområden,Centre for Economic Demography,Lund University School of Economics and Management, LUSEM,Department of Economic History,Lund University School of Economics and Management, LUSEM,LU Profile Area: Human rights,Lund University Profile areas
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- Kravdal, Øystein (author)
- University of Oslo
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- Martikainen, Pekka (author)
- Max Planck Institute for Demographic Research,University of Helsinki
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- Myrskylä, Mikko (author)
- University of Helsinki,Max Planck Institute for Demographic Research
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- Barclay, Kieron, 1986- (author)
- Uppsala universitet,Stockholm University,Stockholms universitet,Sociologiska institutionen,Max Planck Institute for Demographic Research, Rostock, Germany; Swedish Collegium for Advanced Study, Uppsala, Sweden,Swedish Collegium for Advanced Study (SCAS),Kollegiet för avancerade studier (SCAS)
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- Goisis, Alice (author)
- University College London
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(creator_code:org_t)
- 2022-11-09
- 2022
- English.
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In: International Journal of Epidemiology. - : Oxford University Press (OUP). - 0300-5771 .- 1464-3685. ; 52:1, s. 156-164
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Abstract
Subject headings
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- Background: Advanced maternal age at birth is considered a risk factor for adverse birth outcomes. A recent study applying a sibling design has shown, however, that the association might be confounded by unobserved maternal characteristics.Methods: Using total population register data on all live singleton births during the period 1999–2012 in Denmark (N = 580 133; 90% population coverage), Norway (N = 540 890) and Sweden (N = 941 403) and from 2001–2014 in Finland (N = 568 026), we test whether advanced maternal age at birth independently increases the risk of low birthweight (LBW) (<2500 g) and pre-term birth (<37 weeks gestation). We estimated within-family models to reduce confounding by unobserved maternal characteristics shared by siblings using three model specifications: Model 0 examines the bivariate association; Model 1 adjusts for parity and sex; Model 2 for parity, sex and birth year.Results: The main results (Model 1) show an increased risk in LBW and pre-term delivery with increasing maternal ages. For example, compared with maternal ages of 26–27 years, maternal ages of 38–39 years display a 2.2, 0.9, 2.1 and 2.4 percentage point increase in the risk of LBW in Denmark, Finland, Norway and Sweden, respectively. The same patterns hold for pre-term delivery.Conclusions: Advanced maternal age is independently associated with higher risk of poor perinatal health outcomes even after adjusting for all observed and unobserved factors shared between siblings.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- SAMHÄLLSVETENSKAP -- Ekonomi och näringsliv -- Ekonomisk historia (hsv//swe)
- SOCIAL SCIENCES -- Economics and Business -- Economic History (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences (hsv//eng)
Keyword
- Maternal age at birth
- birth outcomes
- sibling design
- Nordic countries
- Maternal age at birth
- birth outcomes
- sibling design
- Nordic countries
Publication and Content Type
- ref (subject category)
- art (subject category)
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