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Saudi Arabian Plants :
Saudi Arabian Plants : A Powerful Weapon against a Plethora of Diseases
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- El-Seedi, Hesham (författare)
- Uppsala universitet,Institutionen för farmaceutisk biovetenskap,Jiangsu Univ, Int Res Ctr Food Nutr & Safety, Zhenjiang 212013, Peoples R China.;Jiangsu Univ, Jiangsu Educ Dept, Int Joint Res Lab Intelligent Agr & Agriprod Proc, Zhenjiang 212013, Peoples R China.;Menoufia Univ, Fac Sci, Dept Chem, Shibin Al Kawm 32512, Egypt.
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- Kotb, Safaa M. (författare)
- Menoufia Univ, Fac Sci, Dept Chem & Microbiol, Shibin Al Kawm 32512, Egypt.
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- Musharraf, Syed G. (författare)
- Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem & Biol Sci, Karachi 75270, Pakistan.
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- Shehata, Awad A. (författare)
- Univ Sadat City, Fac Vet Med, Avian & Rabbit Dis Dept, Sadat City 32897, Egypt.
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- Guo, Zhiming (författare)
- Jiangsu Univ, Sch Food & Biol Engn, Zhenjiang 212013, Peoples R China.
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- Alsharif, Sultan M. (författare)
- Taibah Univ, Fac Sci, Biol Dept, Al Madinah 887, Saudi Arabia.
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- Saeed, Aamer (författare)
- Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan.
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- Hamdi, Omer A. A. (författare)
- Univ Khartoum, Fac Sci, Dept Chem, Khartoum 11115, North Sudan.
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- Tahir, Haroon Elrasheid (författare)
- Jiangsu Univ, Sch Food & Biol Engn, Zhenjiang 212013, Peoples R China.
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- Alnefaie, Rasha (författare)
- Al Baha Univ, Dept Biol, Facul Sci, Albaha 65779, Saudi Arabia.
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- Verpoorte, Rob (författare)
- Leiden Univ, Inst Biol, Nat Prod Lab, POB 9505, NL-2300 RA Leiden, Netherlands.
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- Khalifa, Shaden A. M. (författare)
- Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut,Stockholm Univ, Wenner Gren Inst, Dept Mol Biosci, SE-10691 Stockholm, Sweden.
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(creator_code:org_t)
- 2022-12-08
- 2022
- Engelska.
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Ingår i: PLANTS. - : MDPI AG. - 2223-7747. ; 11:24
- Relaterad länk:
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https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- The kingdom of Saudi Arabia (SA) ranks fifth in Asia in terms of area. It features broad biodiversity, including interesting flora, and was the historical origin of Islam. It is endowed with a large variety of plants, including many herbs, shrubs, and trees. Many of these plants have a long history of use in traditional medicine. The aim of this review is to evaluate the present knowledge on the plants growing in SA regarding their pharmacological and biological activities and the identification of their bioactive compounds to determine which plants could be of interest for further studies. A systematic summary of the plants’ history, distribution, various pharmacological activities, bioactive compounds, and clinical trials are presented in this paper to facilitate future exploration of their therapeutic potential. The literature was obtained from several scientific search engines, including Sci-Finder, PubMed, Web of Science, Google Scholar, Scopus, MDPI, Wiley publications, and Springer Link. Plant names and their synonyms were validated by ‘The Plant List’ on 1 October 2021. SA is home to approximately 2247 plant species, including native and introduced plants that belong to 142 families and 837 genera. It shares the flora of three continents, with many unique features due to its extreme climate and geographical and geological conditions. As plants remain the leading supplier of new therapeutic agents to treat various ailments, Saudi Arabian plants may play a significant role in the fight against cancer, inflammation, and antibiotic-resistant bacteria. To date, 102 active compounds have been identified in plants from different sites in SA. Plants from the western and southwestern regions have been evaluated for various biological activities, including antioxidant, anti-cancer, antimicrobial, antimalarial, anti-inflammatory, anti-glycation, and cytotoxic activities. The aerial parts of the plants, especially the leaves, have yielded most of the bioactive compounds. Most bioactivity tests involve in vitro assessments for the inhibition of the growth of tumour cell lines, and several compounds with in vitro antitumour activity have been reported. More in-depth studies to evaluate the mode of action of the compounds are necessary to pave the way for clinical trials. Ecological and taxonomical studies are needed to evaluate the flora of SA, and a plan for the conservation of wild plants should be implemented, including the management of the protection of endemic plants.
Ämnesord
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
- NATURVETENSKAP -- Biologi -- Botanik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Botany (hsv//eng)
Nyckelord
- Saudi Arabian plants
- distribution
- anti-inflammation
- anti-cancer
- antibiotic resistance
- active compounds
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El-Seedi, Hesham
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Kotb, Safaa M.
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Musharraf, Syed ...
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Shehata, Awad A.
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Guo, Zhiming
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Alsharif, Sultan ...
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Saeed, Aamer
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Hamdi, Omer A. A ...
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Tahir, Haroon El ...
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Alnefaie, Rasha
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Verpoorte, Rob
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Khalifa, Shaden ...
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- NATURVETENSKAP
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Stockholms universitet
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