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  • Wienicke, Frederik J.Department of Clinical Psychology, Behavioural Science Institute, Radboud University, Nijmegen, Netherlands (author)

Efficacy and moderators of short-term psychodynamic psychotherapy for depression : A systematic review and meta-analysis of individual participant data

  • Article/chapterEnglish2023

Publisher, publication year, extent ...

  • Elsevier,2023
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:su-217320
  • https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-217320URI
  • https://doi.org/10.1016/j.cpr.2023.102269DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-193638URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:152553072URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:for swepub-publicationtype

Notes

  • Recruitment of individual participant data for this work was supported by a Fund for Psychoanalytic Research of the American Psychoanalytic Association [no grant number]. This study was further financed by the Netherlands Organization of Scientific Research (NWO): 016.Veni.195.2156806.
  • Funding: Fund for Psychoanalytic Research of the American Psycho-analytic Association; Netherlands Organization of Scientific Research (NWO) [016]
  • Background: Short-term psychodynamic psychotherapy (STPP) is frequently used to treat depression, but it is unclear which patients might benefit specifically. Individual participant data (IPD) meta-analyses can provide more precise effect estimates than conventional meta-analyses and identify patient-level moderators. This IPD meta-analysis examined the efficacy and moderators of STPP for depression compared to control conditions.Methods: PubMed, PsycInfo, Embase, and Cochrane Library were searched September 1st, 2022, to identify randomized trials comparing STPP to control conditions for adults with depression. IPD were requested and analyzed using mixed-effects models.Results: IPD were obtained from 11 of the 13 (84.6%) studies identified (n = 771/837, 92.1%; mean age = 40.8, SD = 13.3; 79.3% female). STPP resulted in significantly lower depressive symptom levels than control conditions at post-treatment (d = −0.62, 95%CI [−0.76, −0.47], p < .001). At post-treatment, STPP was more efficacious for participants with longer rather than shorter current depressive episode durations.Conclusions: These results support the evidence base of STPP for depression and indicate episode duration as an effect modifier. This moderator finding, however, is observational and requires prospective validation in future large-scale trials.

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  • Beutel, Manfred E.Department of Psychosomatic Medicine and Psychotherapy, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany (author)
  • Zwerenz, RüdigerDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany (author)
  • Brähler, ElmarDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany; Integrated Research and Treatment Center Adiposity Diseases, Behavioral Medicine Research Unit, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Leipzig, Germany (author)
  • Fonagy, PeterDepartment of Clinical, Educational and Health Psychology, University College London, London, UK (author)
  • Luyten, PatrickDepartment of Clinical, Educational and Health Psychology, University College London, London, UK; Faculty of Psychology and Educational Sciences, University of Leuven, Leuven, Belgium (author)
  • Constantinou, MatthewDepartment of Clinical, Educational and Health Psychology, University College London, London, UK (author)
  • Barber, Jacques P.Gordon F. Derner School of Psychology, Adelphi University, Garden City, NY, USA (author)
  • McCarthy, Kevin S.Department of Psychology, Chestnut Hill College, Philadelphia, PA, USA; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA (author)
  • Solomonov, NiliWeill Cornell Institute of Geriatric Psychiatry, Weill Cornell Medicine, New York, NY, USA (author)
  • Cooper, Peter J.School of Psychology and Clinical Language Science, University of Reading, Reading, UK (author)
  • De Pascalis, LeonardoDepartment of Psychological Science, University of Liverpool, Liverpool, UK; Department of Psychology, University of Bologna, Bologna, Italy (author)
  • Johansson, Robert,1978-Stockholms universitet,Klinisk psykologi,Department of Psychology, Stockholm University, Stockholm, Sweden(Swepub:su)rojo4696 (author)
  • Andersson, Gerhard,Professor,1988-Karolinska Institutet,Linköpings universitet,Psykologi,Filosofiska fakulteten,Institutionen för biomedicinska och kliniska vetenskaper,Medicinska fakulteten,Region Östergötland, Öron- näsa- och halskliniken,Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden,Internet, health and clinical psychology research group(Swepub:liu)geran87 (author)
  • Lemma, AlessandraAnna Freud National Center for Children and Families, London, UK (author)
  • Town, Joel M.Center for Emotions & Health, Dalhousie University, Halifax, Nova Scotia, Canada (author)
  • Abbass, Allan A.Center for Emotions & Health, Dalhousie University, Halifax, Nova Scotia, Canada (author)
  • Ajilchi, BitaDepartment of Psychology, Faculty of Human Science, Science and Research Branch, Islamic Azad University, Tehran, Iran (author)
  • Connolly Gibbons, Mary BethDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA (author)
  • López-Rodríguez, JaimeNational Institute of Psychiatry, Mexico City, Mexico (author)
  • Villamil-Salcedo, ValerioNational Institute of Psychiatry, Mexico City, Mexico (author)
  • Maina, GiuseppeDepartment of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; Psychiatric Unit, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy (author)
  • Rosso, GianlucaDepartment of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; Psychiatric Unit, San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy (author)
  • Twisk, Jos W. R.Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (author)
  • Burk, William J.Department of Developmental Psychology, Behavioural Science Institute, Radboud University, Nijmegen, the Netherlands (author)
  • Spijker, JanDepartment of Clinical Psychology, Behavioural Science Institute, Radboud University, Nijmegen, Netherlands; Depression Expertise Center, Pro Persona Mental Health Care, Nijmegen, the Netherlands (author)
  • Cuijpers, PimDepartment of Clinical, Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands (author)
  • Driessen, EllenDepartment of Clinical Psychology, Behavioural Science Institute, Radboud University, Nijmegen, Netherlands; Depression Expertise Center, Pro Persona Mental Health Care, Nijmegen, the Netherlands (author)
  • Department of Clinical Psychology, Behavioural Science Institute, Radboud University, Nijmegen, NetherlandsDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany (creator_code:org_t)

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  • In:Clinical Psychology Review: Elsevier1010272-73581873-7811

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