Sökning: id:"swepub:oai:DiVA.org:su-23832" >
Magnetic resonance ...
-
Andersson, AugustStockholms universitet,Institutionen för biokemi och biofysik
(författare)
Magnetic resonance investigations of lipid motion in isotropic bicelles
- Artikel/kapitelEngelska2005
Förlag, utgivningsår, omfång ...
-
2005-07-23
-
American Chemical Society (ACS),2005
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:su-23832
-
https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-23832URI
-
https://doi.org/10.1021/la0513003DOI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
The dynamics of DMPC in different isotropic bicelles have been investigated by NMR and EPR methods. The local dynamics were obtained by interpretation of 13C NMR relaxation measurements of DMPC in the bicelles, and these results were compared to EPR spectra of spin-labeled lipids. The overall size of the bicelles was investigated by PFG NMR translational diffusion measurements. The dynamics and relative sizes were compared among three different bicelles: [DMPC]/[DHPC] = 0.25, [DMPC]/[DHPC] = 0.5, and [DMPC]/[CHAPS] = 0.5. The local motion is found to depend much more strongly on the choice of the detergent, rather than the overall size of the bicelle. The results provide an explanation for differences in apparent dynamics for different peptides, which are bound to bicelles. This in turn determines under what conditions reasonable NMR spectra can be observed. A model is presented in which extensive local motion, in conjunction with the overall size, affects the spectral properties. An analytical expression for the size dependence of the bicelles, relating the radius of the bilayer region with physical properties of the detergent and the lipid, is also presented.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Mäler, LenaStockholms universitet,Institutionen för biokemi och biofysik(Swepub:su)maler
(författare)
-
Stockholms universitetInstitutionen för biokemi och biofysik
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Journal of the American Chemical Society: American Chemical Society (ACS)21:7, s. 7702-77090002-78631520-5126
-
Ingår i:Langmuir: American Chemical Society (ACS)21:7, s. 7702-77090743-74631520-5827
Internetlänk
Hitta via bibliotek
Till lärosätets databas