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  • Hogberg, Liselotte (författare)

Age- and serogroup-related differences in observed durations of nasopharyngeal carriage of penicillin-resistant pneumococci

  • Artikel/kapitelEngelska2007

Förlag, utgivningsår, omfång ...

  • 2007
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:su-56601
  • https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-56601URI
  • https://doi.org/10.1128/JCM.01913-06DOI
  • https://lup.lub.lu.se/record/669698URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:14011499URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • authorCount :6
  • Using data from an ongoing Swedish intervention project, the observed durations of nasopharyngeal carriage of penicillin-nonsusceptible Streptococcus pneumoniae (PNSP) (MIC of penicillin G of >= 0.5 mu g/ml) stratified by both pneumococcal serogroup and age of the carrier were compared. The means and 95% confidence intervals (CIs) were estimated by fitting a gamma distribution to the observed duration of carriage for each age and serogroup stratum. The mean observed duration of carriage for all cases was 37 days (95% CI, 35 to 38 days). Children below the age of 5 years carried PNSP for significantly longer periods (43 days; 95% CI, 41 to 45 days) compared with older individuals (25 days; 95% CI, 24 to 27 days). There were also differences within the group of cases below the age of 5 years, as the duration of carriage became significantly shorter for each increasing age step: < 1, 1 to 2, and 3 to 4 years. In addition, patients < 5 years of age carried serogroups 9 and 14 for significantly shorter periods than groups 6 and 23. Serogroup 9 was also carried for significantly shorter periods than group 19. For patients aged 5 years or older, no significant difference in carriage duration for different ages or serogroups could be noted. As young children have the longest duration of PNSP carriage, interventions aiming to reduce the prevalence in this group are of great importance. The results highlight the importance of taking both serogroup and age of the carriers into account when studying the dynamics of pneumococcal transmission in young children.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Geli, PatriciaStockholms universitet,Matematiska institutionen (författare)
  • Ringberg, HåkanLund University,Lunds universitet,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)inf-hri (författare)
  • Melander, Eva (författare)
  • Lipsitch, Marc (författare)
  • Ekdahl, KarlKarolinska Institutet (författare)
  • Stockholms universitetMatematiska institutionen (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Journal of Clinical Microbiology45:3, s. 948-9520095-11371098-660X

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