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European Vaccine In...
European Vaccine Initiative : lessons from developing malaria vaccines
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Geels, Mark J (author)
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Imoukhuede, Egeruan B (author)
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Imbault, Nathalie (author)
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van Schooten, Harry (author)
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McWade, Terry (author)
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- Troye-Blomberg, Marita (author)
- Stockholms universitet,Avdelningen för immunologi
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Dobbelaer, Roland (author)
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Craig, Alister G (author)
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Leroy, Odile (author)
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(creator_code:org_t)
- 2014-01-09
- 2011
- English.
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In: Expert Review of Vaccines. - : Informa UK Limited. - 1476-0584 .- 1744-8395. ; 10:12, s. 1697-1708
- Related links:
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https://archive.lstm...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- For over 10 years, the European Vaccine Initiative (EVI; European Malaria Vaccine Initiative until 2009) has contributed to the development of 24 malaria candidate vaccine antigens with 13 vaccine candidates being advanced into Phase I clinical trials, two of which have been transitioned for further clinical development in sub-Saharan Africa. Since its inception the EVI organization has operated as a funding agency, but with a clear service-oriented strategy. The scientific successes and difficulties encountered during these years and how these efforts have led to standardization and harmonization in vaccine development through large-scale European consortia are discussed. In the future, the EVI will remain instrumental in the pharmaceutical and clinical development of vaccines against ?diseases of poverty? with a continued focus on malaria. EVI will continue to focus on funding and managing preclinical evaluation up to Phase I/II clinical trials and strengthening the vaccine-development infrastructure in Europe, albeit with a global orientation.
Subject headings
- NATURVETENSKAP -- Biologi -- Immunologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Immunology (hsv//eng)
Keyword
- diseases of poverty; EMVI; EVI; malaria; PDP; research infrastructure; vaccine
Publication and Content Type
- ref (subject category)
- art (subject category)
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