SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Bergman Åke)
 

Sökning: WFRF:(Bergman Åke) > Scientific Opinion ...

Scientific Opinion on Tetrabromobisphenol A (TBBPA) and its derivatives in food : EFSA Panel on Contaminants in the Food Chain (CONTAM)

Alexander, Jan (författare)
Benford, Diane (författare)
Boobis, Alan (författare)
visa fler...
Bergman, Åke (författare)
Stockholms universitet,Avdelningen för miljökemi
visa färre...
 (creator_code:org_t)
2011-12-19
2011
Engelska.
Ingår i: EFSA Journal. - : Wiley. - 1831-4732. ; 9:12, s. 2477-
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • EFSA was asked by the European Commission to deliver a scientific opinion on tetrabromobisphenol A (TBBPA) and its derivatives in food. TBBPA and its derivatives are widely used as flame retardants. TBBPA is primarily used as reactive flame retardant covalently bound to epoxy and polycarbonate resins. TBBPA derivatives are used as either reactive or additive intermediates in polymer manufacture. Data from the analysis of TBBPA in 344 food samples were submitted to EFSA by two European countries (Norway and Spain), covering the period from 2007 to 2010. All samples were in the food group “Fish and other seafood”, and all analytical results were reported as less than the limit of quantification (LOQ) (about 1 ng/g wet weight). Toxicological studies with TBBPA have been carried out using different experimental designs with single or repeated administration during gestation, postnatally or in adulthood. The main target is thyroid hormone homeostasis. TBBPA is not genotoxic. There are no indications that TBBPA might be carcinogenic. The Panel on Contaminants in the Food Chain (CONTAM Panel) identified a lower confidence limit for a benchmark response of 10 % (BMDL10) of 16 mg/kg b.w. reported for changes in thyroid hormones as the critical reference point. Due to the limitations and uncertainties in the database, the CONTAM Panel concluded that it was inappropriate to use this BMDL to establish a health based guidance value, and therefore used a margin of exposure (MOE) approach for the health risk assessment of TBBPA. In view of the large MOEs, the CONTAM Panel concluded that current dietary exposure to TBBPA in the European Union does not raise a health concern. Also exposure of infants via human milk does not raise a health concern. Additional exposure, particularly of young children, to TBBPA from house dust is unlikely to raise a health concern.

Ämnesord

NATURVETENSKAP  -- Kemi -- Annan kemi (hsv//swe)
NATURAL SCIENCES  -- Chemical Sciences -- Other Chemistry Topics (hsv//eng)

Nyckelord

Tetrabromobisphenol A
TBBPA
TBBPA derivatives
occurrence
food
toxicology
human exposure
risk assessment

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...
Alexander, Jan
Benford, Diane
Boobis, Alan
Bergman, Åke
Om ämnet
NATURVETENSKAP
NATURVETENSKAP
och Kemi
och Annan kemi
Artiklar i publikationen
EFSA Journal
Av lärosätet
Stockholms universitet

Sök utanför SwePub

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy