Sökning: id:"swepub:oai:DiVA.org:su-79139" >
Quantifying tumour ...
-
Toma-Dasu, IulianaKarolinska Institutet,Stockholms universitet,Medicinsk strålningsfysik (tills m KI),Stockholm University and Karolinska Institutet
(författare)
Quantifying tumour hypoxia by PET imaging : a theoretical analysis
- Artikel/kapitelEngelska2009
Förlag, utgivningsår, omfång ...
-
Boston, MA :Springer US,2009
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:su-79139
-
https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-79139URI
-
https://doi.org/10.1007/978-0-387-85998-9_40DOI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-22682URI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-71980URI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:118161031URI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
Information on tumour oxygenation could be obtained from various imaging methods, but the success of incorporating it into treatment planning depends on the accuracy of quantifying it. This study presents a theoretical analysis of the efficiency of measuring tumour hypoxia by PET imaging. Tissue oxygenations were calculated for ranges of biologically relevant physiological parameters and were then used to simulate PET images for markers with different uptake characteristics. The resulting images were used to calculate dose distributions that could lead to predefined tumour control levels. The results have shown that quantification of tumour hypoxia with PET may lead to different values according to the tracer used and the tumour site investigated. This would in turn be reflected into the dose distributions recommended by the optimisation algorithms. However, irrespective of marker-specific differences, focusing the radiation dose to the hypoxic areas appears to reduce the average tumour dose needed to achieve a certain control level.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Daşu, AlexandruUmeå universitet,Radiofysik,Norrlands University Hospital(Swepub:liu)aleda92
(författare)
-
Brahme, AndersKarolinska Institutet
(författare)
-
Liss, P
(författare)
-
Hansell, P
(författare)
-
Bruley, DF
(författare)
-
Harrison, DK
(författare)
-
Stockholms universitetMedicinsk strålningsfysik (tills m KI)
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Advances in Experimental Medicine and BiologyBoston, MA : Springer US645, s. 267-2720065-25982214-8019
Internetlänk
Hitta via bibliotek
Till lärosätets databas