Pharmacological evaluation of benzimidazole derivatives with potential antiviral and antitumor activity

• In recent years the synthesis of benzimidazole and its derivatives has attracted the attention of many organic chemists because of the compounds' interesting biological activity and the crucial importance of the benzimidazole unit in the function of these biologically important molecules. Benzimidazole-based polyheterocyclic compounds have several interesting biological properties. Simple synthetic strategies leading to benzimidazole-based fused polyheterocyclic systems and the antiviral and anticancer biological activity of the compounds are surveyed in this review article.

Subject headings

NATURVETENSKAP  -- Kemi (hsv//swe)

NATURAL SCIENCES  -- Chemical Sciences (hsv//eng)

Keyword

Benzimidazole derivatives

Combinatorial synthesis

Microwave-assisted synthesis

Heterocycles

Topoisomerase inhibitors

Protein kinase inhibitor

Antitumor

Antiviral

Publication and Content Type

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