Beta-blockers and thoracic epidural analgesia. Cardioprotective and synergistic effects

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: WFRF:(Östman S.) > Beta-blockers and t...

Details
MARC

Reiz, S.Umeå universitet,Anestesiologi och intensivvård (author)

Beta-blockers and thoracic epidural analgesia. Cardioprotective and synergistic effects

Article/chapterEnglish1982

Publisher, publication year, extent ...

1982
printrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:umu-100619
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100619URI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Reiz, S Haggmark, S Rydvall, A Ostman, M Denmark Acta anaesthesiologica Scandinavica. Supplementum Acta Anaesthesiol Scand Suppl. 1982;76:54-61.
Seven groups of patients with and without hypertension or with ischaemic heart disease, treated with different beta blockers were investigated to study the circulatory effects of neurolept anaesthesia alone or combined with thoracic epidural analgesia from T4 to T12/L2 during abdominal surgery. The combination of thoracic epidural analgesia and neurolept anaesthesia in hypertensive subjects treated with non-cardioselective beta blockers induced slightly lower blood pressure than measured in similar patients on cardioselective beta blockers with neurolept anaesthesia only. Patients on non-selective beta blockers with intrinsic stimulatory activity (ISA) had higher blood pressure and heart rate after neurolept anaesthesia induction than patients on cardioselective blockers. During surgery, heart rate remained at a higher level in the patients treated with ISA blockers, whereas blood pressure increased to the same level as in patients with cardioselective blockers. Cardiovascular stability was, however, best maintained in the epidural group, where myocardial energy expenditure during maximal surgical stress was comparable to that in a group of healthy subjects with the same format of anaesthesia and significantly lower than in healthy subjects with neurolept anaesthesia alone. No circulatory side effects of the combination of thoracic epidural analgesia and beta blockade were seen. In patients with ischaemic heart disease, with or without non-selective beta blockade, similar haemodynamic changes were recorded following neurolept anaesthesia. During maximal surgical stress, unmasking of alpha adrenergic activity with marked rise in blood pressure was seen in the beta-blocked patients. Despite the more accelerated haemodynamic changes in the blocked patients, a lower increase in myocardial oxygen consumption was recorded compared with the non-blocked patients.(ABSTRACT TRUNCATED AT 250 WORDS)

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Anestesi och intensivvård hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Anesthesiology and Intensive Care hsv//eng
Adrenergic beta-Antagonists/*therapeutic use
*Analgesia
Epidural
Coronary Disease/drug therapy/physiopathology/*surgery
Hemodynamics
Humans
Hypertension/drug therapy/physiopathology/*surgery

Added entries (persons, corporate bodies, meetings, titles ...)

Häggmark, S.Umeå universitet,Anestesiologi och intensivvård(Swepub:umu)kaso0008 (author)
Rydvall, A.Umeå universitet,Anestesiologi och intensivvård(Swepub:umu)anry0024 (author)
Östman, M.Umeå universitet,Anestesiologi och intensivvård (author)
Umeå universitetAnestesiologi och intensivvård (creator_code:org_t)

Related titles

In:Acta Anaesthesiol Scand Suppl76, s. 54-61

Internet link

Find in a library

Acta Anaesthesiol Scand Suppl (Search for host publication in LIBRIS)

To the university's database

Find more in SwePub

By the author/editor: Reiz, S.; Häggmark, S.; Rydvall, A.; Östman, M.

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Anesthesiology a ...

Articles in the publication: Acta Anaesthesio ...

By the university: Umeå University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se