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Improved adherence ...
Improved adherence and spreading of Saos-2 cells on polypropylene surfaces achieved by surface texturing and carbon nitride coating.
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- Myllymaa, Katja (author)
- Microsensor Laboratory, School of Engineering and Technology, Savonia University of Applied Sciences, Kuopio, Finland; Department of Physics, University of Kuopio, Kuopio, Finland
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- Myllymaa, Sami (author)
- Department of Physics, University of Kuopio, Kuopio, Finland
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- Korhonen, Hannu (author)
- Department of Physics, University of Kuopio, Kuopio, Finland
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- Lammi, Mikko, 1961- (author)
- Departmentof Applied Biotechnology, University of Kuopio, Kuopio; Biocenter Kuopio, University of Kuopio, Kuopio, Finland,Chondrogenic and Osteogenic Differentiation Group
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- Saarenpää, Hanna (author)
- Department of Chemistry, University of Joensuu, Joensuu, Finland
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- Suvanto, Mika (author)
- Department of Chemistry, University of Joensuu, Joensuu, Finland
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- Pakkanen, Tapani (author)
- Department of Chemistry, University of Joensuu, Joensuu, Finland
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- Tiitu, Virpi (author)
- Department of Biomedicine, Anatomy, University of Kuopio, Kuopio, Finland
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- Lappalainen, Reijo (author)
- Department of Physics, University of Kuopio, Kuopio, Finland
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(creator_code:org_t)
- 2009-06-09
- 2009
- English.
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In: Journal of materials science. Materials in medicine. - : Springer. - 0957-4530 .- 1573-4838. ; 20:11, s. 2337-2347
- Related links:
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http://link.springer...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- The adhesion and contact guidance of human primary osteogenic sarcoma cells (Saos-2) were characterized on smooth, microstructured (MST) and micro- and nano-structured (MNST) polypropylene (PP) and on the same samples with a silicon-doped carbon nitride (C(3)N(4)-Si) coating. Injection molding was used to pattern the PP surfaces and the coating was obtained by using ultra-short pulsed laser deposition (USPLD). Surfaces were characterized using atomic force microscopy and surface energy components were calculated according to the Owens-Wendt model. The results showed C(3)N(4)-Si coated surfaces to be significantly more hydrophilic than uncoated ones. In addition, there were 86% more cells in the smooth C(3)N(4)-Si coated PP compared to smooth uncoated PP and 551%/476% more cells with MST/MNST C(3)N(4)-Si coated PP than could be obtained with MST/MNST uncoated PP. Thus the adhesion, spreading and contact guidance of osteoblast-like cells was effectively improved by combining surface texturing and deposition of osteocompatible C(3)N(4)-Si coating.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk material- och protesteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Materials (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi -- Biomaterialvetenskap (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology -- Biomaterials Science (hsv//eng)
Keyword
- Surfaces and Interfaces
- Thin Films
- Characterization and Evaluation of Materials
- Metallic Materials
- Ceramics
- Glass
- Composites
- Natural Methods
- Polymer Sciences
- Biomaterials
- cell research
- cellforskning
- Materials Science
- materialvetenskap
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Myllymaa, Katja
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Myllymaa, Sami
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Korhonen, Hannu
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Lammi, Mikko, 19 ...
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Saarenpää, Hanna
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Suvanto, Mika
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show more...
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Pakkanen, Tapani
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Tiitu, Virpi
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Lappalainen, Rei ...
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- About the subject
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Medical Engineer ...
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and Medical Material ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Medical Biotechn ...
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and Biomaterials Sci ...
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Umeå University