Chemosensory perception, symptoms and autonomic responses during chemical exposure in multiple chemical sensitivity

Andersson, LinusHögskolan i Gävle,Arbetshälsovetenskap,Centrum för belastningsskadeforskning (författare)

Purpose: Multiple chemical sensitivity (MCS) is a prevalent medically unexplained symptom characterized by symptom reactions to everyday chemical exposure below hygienic thresholds. The aim of this study was to investigate the expressions of hyper-reactivity in MCS during whole-body exposure to low concentrations of the odorant n-butanol.Methods: We exposed 18 participants with MCS and 18 non-ill controls to a low concentration of the odorantn-butanol using an exposure chamber. The first 10 min constituted blank exposure, after which then-butanol concentration increased and reached a plateau at 11.5 mg/m3.Results: MCS participants, compared with controls, reported greater perceived odor intensities, more unpleasantness to the exposure and increasing symptoms over time. MCS participants also expressed higher pulse rate and lower pulse rate variability than controls did. No group differences were found for breathing rate or tonic electrodermal activity responses.Conclusions: We conclude that MCS sufferers differ from healthy controls in terms of autonomic responses, symptoms and chemosensory perception during chemical exposure.

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Annan hälsovetenskap hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Other Health Sciences hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Arbetsmedicin och miljömedicin hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Occupational Health and Environmental Health hsv//eng
Multiple chemical sensitivity
Chemical intolerance
Environmental intolerance
Olfaction
Autonomic rvous system
ROGATIS LR
1976
BRITISH JOURNAL OF PSYCHIATRY
V128
P280 tthoeft Michael
2006
JOURNAL OF ABNORMAL PSYCHOLOGY
V115
P397 rie Thi Dao Tran
2013
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
V216

Claeson, Anna-Sara,1974-Umeå universitet,Institutionen för psykologi,Department of Psychology, Umeå University, Umeå, Sweden(Swepub:umu)ancl0002 (författare)
Dantoft, Thomas MeinertzDanish Research Centre for Chemical Sensitivities, Copenhagen University Hospital Gentofte, Gentofte, Denmark; Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, Lyngby, Denmark (författare)
Skovbjerg, SineDanish Research Centre for Chemical Sensitivities, Copenhagen University Hospital Gentofte, Gentofte, Denmark (författare)
Lind, Nina,1989-Umeå universitet,Institutionen för psykologi,Department of Psychology, Umeå University, Umeå, Sweden(Swepub:umu)nili0024 (författare)
Nordin, Steven,1960-Umeå universitet,Institutionen för psykologi,Department of Psychology, Umeå University, Umeå, Sweden(Swepub:umu)stno0002 (författare)
Högskolan i GävleArbetshälsovetenskap (creator_code:org_t)

Ingår i:International Archives of Occupational and Environmental Health: Springer89:1, s. 79-880340-01311432-1246

Av författaren/redakt...: Andersson, Linus; Claeson, Anna-Sa ...; Dantoft, Thomas ...; Skovbjerg, Sine; Lind, Nina, 1989 ...; Nordin, Steven, ...

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