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Identification of p...
Identification of potentially toxic compounds in complex extracts of environmental samples using GC-MS and multivariate data analysis
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- Bergknut, Magnus (author)
- Umeå universitet,Kemiska institutionen
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Kucera, Adam (author)
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- Frech, Kristina (author)
- Umeå universitet,Kemiska institutionen
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Andersson, Erika (author)
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Engwall, Magnus (author)
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Rannung, Ulf (author)
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Koci, Vladimir (author)
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- Andersson, Patrik (author)
- Umeå universitet,Kemiska institutionen
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- Haglund, Peter (author)
- Umeå universitet,Kemiska institutionen
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- Tysklind, Mats (author)
- Umeå universitet,Kemiska institutionen
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(creator_code:org_t)
- 2007
- 2007
- English.
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In: Environmental Toxicology and Chemistry. - 0730-7268 .- 1552-8618. ; 26:2, s. 208-17
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- In this study, we examined 31 samples of varying chemical composition, including samples of soils from gasworks, coke production sites, and sites where wood preservatives were heavily used; ash and soot from municipal solid waste incinerators; antiskid sand; and dust from areas with heavy road traffic. The samples were comprehensively chemically characterized, especially their polycyclic aromatic compound contents, using gas chromatography–time-of-flight mass spectrometry, whereas their biological effects were assessed using dehydrogenase activity, root growth (Hordeum vulgare), reproduction of springtails (Folsomia candida), algal growth (Desmodesmus subspicatus), germinability (Sinapis alba), Vibrio fischeri, DR-CALUX, and Ames Salmonella assays. The number of compounds detected in the samples ranged from 123 to 527. Using the multivariate regression technique of partial-least-squares projections to latent structures, it was possible to find individual compounds that exhibited strong correlations with the different biological responses. Some of the results, however, indicate that a broader chemical characterization may be needed to identify all the compounds that may cause the measured biological responses.
Keyword
- Soil
- Polycyclic aromatic compounds
- Bioassay
- Multivariate techniques
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Bergknut, Magnus
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Kucera, Adam
-
Frech, Kristina
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Andersson, Erika
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Engwall, Magnus
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Rannung, Ulf
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show more...
-
Koci, Vladimir
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Andersson, Patri ...
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Haglund, Peter
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Tysklind, Mats
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show less...
- Articles in the publication
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Environmental To ...
- By the university
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Umeå University